Results 51 to 60 of about 673,085 (305)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Analyzing the Triad Diagnosis Requirement for Autism in Arkansas [PDF]

open access: yes, 2020
Autism Spectrum Disorder (ASD) is a developmental disorder that has steadily increased in incidence and prevalence over the last ten years. While the disorder can be diagnosed as early as two years of age, most children do not receive a diagnosis until ...
Barrientos-Figueroa, Liliana
core   +2 more sources

Population Health Solutions for Assessing Cognitive Impairment in Geriatric Patients. [PDF]

open access: yes, 2018
In December 2017, the National Academy of Neuropsychology convened an interorganizational Summit on Population Health Solutions for Assessing Cognitive Impairment in Geriatric Patients in Denver, Colorado. The Summit brought together representatives of a
Adler, Deb   +38 more
core   +2 more sources

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Concentrated transdiagnostic and cross-disciplinary group treatment for patients with depression and with anxiety: a pilot study

open access: yesBMC Psychiatry, 2022
Background A number of treatment approaches have shown efficacy for depression and/or anxiety, yet there is a paucity of research on potentially cost-effective concentrated approaches.
Gerd Kvale   +6 more
doaj   +1 more source

Challenges for the Evaluation of the P.I.P.P.I. - Programme of Intervention for Prevention of Institutionalisation: between Partecipative and Experimental Pathways [PDF]

open access: yes, 2017
Evaluation is constantly requested by governments and decision-makers, to prove that social policies and actions undertaken are effective in responding to problems.
Colombini, Sara   +3 more
core  

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

The TRIPLEX study: use of patient-derived tumor organoids as an innovative tool for precision medicine in triple-negative breast cancer

open access: yesBMC Cancer, 2023
Background Triple negative breast cancers (TNBC) account for approximately 15% of all breast cancers and are associated with a shorter median survival mainly due to locally advanced tumor and high risk of metastasis. The current neoadjuvant treatment for
Jordane Divoux   +25 more
doaj   +1 more source

How BRCA1 deficiency affects emergency granulopoeisis in cells [PDF]

open access: yes, 2016
BRCA1 mutation carriers are predisposed to breast and ovarian cancer. Chemotherapy is a common treatment used in breast cancer patients. However, chemotherapy can cause damage to bone marrow.
Dhar, Shilpa
core   +2 more sources

Home - About - Disclaimer - Privacy