Results 131 to 140 of about 18,639,208 (342)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Snakebite envenoming in Africa remains widely neglected and demands multidisciplinary attention

open access: yesNature Communications
Snakebite envenoming can cause morbidity, permanent disability or death but treatment and prevention thereof remains highly inadequate in Africa. Overcoming structural and financial barriers that impede existing initiatives to improve medical management ...
Philipp Berg   +4 more
doaj   +1 more source

First-year college students’ interest in trying dissolvable tobacco products

open access: green, 2013
Mark Wolfson   +6 more
openalex   +2 more sources

Skin as a Potential Organ for Ectopic Monoclonal Antibody Production11The authors declared not to have a conflict of interest. [PDF]

open access: bronze, 2002
Danièle Noël   +4 more
openalex   +1 more source

Financial Conflicts of Interest in Public Comments on Medicare National Coverage Determinations of Medical Devices

open access: green, 2023
Angela Lu   +6 more
openalex   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Interest rate smoothing [PDF]

open access: yes
Interest rates ; Monetary policy - United ...
Carl E. Walsh
core  

Contraceptive use in France in 2012 and 2022: a descriptive analysis of two repeated nationwide cross-sectional studiesResearch in context

open access: yesThe Lancet Regional Health. Europe
Summary: Background: A decrease in oral contraceptive use, newly available methods, and the emerging role of midwives suggested meaningful changes in contraception use in France.
Lorraine Poncet   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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