Results 221 to 230 of about 11,227,343 (266)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Correction: Attitude towards sports, psychological resilience and life engagement: a study on earthquake victims. [PDF]

Front Public Health
Tek T, Özsari A, Tilki M, Deli ṢC, Çetin MÇ.   +4 more
europepmc   +1 more source

Growing public interest and regional disparities of cardiorenal syndrome in the United States. [PDF]

Front Digit Health
Schlesinger RP, Kashani KB, Thongprayoon C, Cheungpasitporn W, Miao J.   +4 more
europepmc   +1 more source

Correction: Templated tibial plateau leveling osteotomy and implant guidance system improves accuracy in novice surgeons: an <i>ex vivo</i> study. [PDF]

Front Vet Sci
Wyatt TJ, Lynch AC, Miniter B.
europepmc   +1 more source

Perspectives of consumer involvement in pre-clinical musculoskeletal research: a cross-sectional survey of consumers and community members. [PDF]

Rheumatol Adv Pract
Ross MH, Thomas CM, Jenkinson B, Doig E, Little CB, McPherson AA, Beanland C, Hodges P, Australia and New Zealand Musculoskeletal Clinical Trials Network (ANZMUSC) Basic Science Special Interest Group, Australia and New Zealand Musculoskeletal Clinical Trials Network (ANZMUSC) Basic Science Special Interest Group .   +9 more
europepmc   +1 more source