Results 251 to 260 of about 18,639,208 (342)

P114: Over-representation of PMS2CL pseudogene interference in PMS2 testing in a non-European cohort

open access: yesGenetics in Medicine Open
Emily Maxwell   +8 more
doaj   +1 more source

Fatal Steam Pop Complicating Investigational SESAME Transcatheter Myotomy Using Off-the-Shelf Equipment. [PDF]

open access: yesCirc Cardiovasc Interv
Lederman RJ   +9 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Investigating the Appeal of Nicotine Pouch Packaging, Flavour, and Nicotine Descriptors Among Adults in the UK: An Online Experiment. [PDF]

open access: yesNicotine Tob Res
Taylor E   +9 more
europepmc   +1 more source

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