Results 21 to 30 of about 7,574,406 (265)

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Equity and capacity to benefit from early access to medicines schemes

International Journal for Equity in Health
Many diseases, especially rare ones, have not gained the attention or support needed to attract dedicated research interest to be able to develop successful medicines.
Sarah J. L. Edwards, Paul Aliu, Joe Brierley, Søren Holm, Peter J. Pitts   +4 more
doaj   +1 more source

Osteonecrosis in sickle cell disease: Contemporary orthopaedic practice and outcomes across African healthcare settings

SICOT-J
Background: Osteonecrosis is a disabling complication of sickle cell disease (SCD), with a disproportionate burden in Africa, where healthcare resources are limited.
Oladeji Emmanuel Olusola, Olayode Oluwatobi, Zubair Abdulahi, Ipomai Vernon, Olayinka Oluwafemi, Okonkwo Patrick, Omerenma Onyeka, Okhifun Gregory, Obakponovwe Oghofori   +8 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

The current state of minimally invasive cardiac surgery in Africa: a systematic review and meta-analysis

The Cardiothoracic Surgeon
Background Globally, the utilisation of minimally invasive techniques has become increasingly prevalent. While traditional open-heart procedures still dominate the landscape, a significant portion of cardiac surgeries are now performed minimally ...
Oluwanifemi O. Akintoye, Bukola G. Adu, Michael J. Otorkpa, Oluwatobi O. Olayode, Samuel Fodop, Peace O. Alemede, Ruth K. Enyong, Feziechi C. Anele, Benjamin I. Omoregbee   +8 more
doaj   +1 more source

The prognostic utility of temporalis muscle thickness measured on magnetic resonance scans in patients with intra-axial malignant brain tumours: A systematic review and meta-analysis

World Neurosurgery: X
Introduction: Sarcopenia is associated with worsened outcomes in solid cancers. Temporalis muscle thickness (TMT) has emerged as a measure of sarcopenia.
Olatomiwa Olukoya, Temidayo Osunronbi, Damilola A. Jesuyajolu, Blossom C. Uwaga, Ayomide Vaughan, Oluwabusayo Aluko, Temitayo O. Ayantayo, Jeremiah O.I. Daniel, Samuel O. David, Habiblah A. Jagunmolu, Alieu Kanu, Ayomide T. Kayode, Tobi N. Olajide, Lewis Thorne   +13 more
doaj   +1 more source

Effectiveness of BNT162b2, mRNA-1273, and ChAdOx1-S vaccines against severe covid-19 outcomes in a nationwide mass vaccination setting: cohort study

BMJ Medicine, 2022
Objective To estimate the effectiveness of the three covid-19 vaccines by Pfizer-BioNTech (BNT162b2), Moderna (mRNA-1273), and Oxford-AstraZeneca (ChAdOx1-S) in people after receiving two doses.Design Cohort study.Setting Nationwide, population based ...
Jérôme Drouin, Alain Weill, Jérémie Botton, Rosemary Dray-Spira, Mahmoud Zureik, Kim Bouillon, Bérangère Baricault, Marie-Joëlle Jabagi, Marion Bertrand, Laura Semenzato, Stéphane Le Vu   +10 more
doaj   +1 more source

Is your “gene of interest” interesting? [PDF]

Developmental Dynamics, 2007
AbstractHas a large‐scale screen turned up a potential gene‐of‐interest that you know nothing about? Your computer is a portal to a wealth of information that can save you valuable time and resources. Freely available data can help to determine whether a particular gene is worthy of further research, and what direction that research should take ...
openaire   +2 more sources

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Prognosis of primary pulmonary adenocarcinoma after surgical resection in small‐breed dogs: 52 cases (2005‐2021)

Journal of Veterinary Internal Medicine, 2023
Background Tumor size is an important prognostic factor in lung cancer in dogs, and the canine lung carcinoma stage classification (CLCSC) recently has been proposed to subdivide tumor sizes.
Masanao Ichimata, Yumiko Kagawa, Keita Namiki, Atsushi Toshima, Yuko Nakano, Fukiko Matsuyama, Eri Fukazawa, Kei Harada, Ryuzo Katayama, Tetsuya Kobayashi   +9 more
doaj   +1 more source