Results 71 to 80 of about 4,321,802 (250)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Conditionality of Political Short‐Termism: A Review of Empirical and Experimental Studies
Politics and GovernancePolitical short-termism prioritizes short-term net policy benefits over long-term benefits and thus can hinder policy investments that impose short-term costs to society to address long-term policy challenges.
Masakazu Ogami
doaj +1 more source
Russia on the Path Towards a New Technology-Industrial Policy: Exciting Prospects and Fatal Traps
Foresight and STI Governance, 2014 The article aims to discuss the practical problems and inconsistencies of industrial policy in Russia since 2000, to analyze positive and negative experiences, and to draw up some lessons which are essential for a new technology-industrial policy ...
Yuri Simachev +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Lifestyle Medicine Interest Groups: Planting Seeds for the Future. [PDF]
Am J Lifestyle Med, 2023 Frates B.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
East/West: Journal of Ukrainian StudiesStatistical data indicates that domestic violence in present-day Ukraine is a particularly acute phenomenon. Urgent policy responses are therefore required on the part of state authorities in order to prevent and combat the problem.
Veronika Puhach, Oleksandr Demianchuk
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Czech Journal of International Relations, 2015 The Lisbon revision of the primary law led to the confirmation of the pre-existing Commission’s commitment to carry out “broad consultations” while preparing European legislative acts.
Markéta Pitrová, Jana Zatloukalová
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source