Results 111 to 120 of about 4,256,497 (306)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The impact of commodity price volatility on fiscal balance and the role of real interest rate. [PDF]

Empir Econ, 2022
Majumder MK, Raghavan M, Vespignani J.
europepmc   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Analisis Pengaruh Nilai Tukar, Tingkat Suku Bunga, dan Produk Domestik Bruto Terhadap Foreign Direct Investment Di Indonesia

Jurnal Nuansa Akademik
The main focus of this study is to analyze the influence of exchange rates, interest rates, and Gross Domestic Product (GDP) on Foreign Direct Investment (FDI) in Indonesia during the period 2004-2024.
Mayiya Putri Evinda, Moehadi Moehadi, Retno Muslinawati   +2 more
doaj   +1 more source

The impact of the US interest rate and oil prices on renewable energy in Turkey: a bootstrap ARDL approach. [PDF]

Environ Sci Pollut Res Int, 2022
Samour A, Pata UK.
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

System Dynamics Models of Online Lending Platform Based on Vensim Simulation Technology and Analysis of Interest Rate Evolution Trend. [PDF]

Comput Intell Neurosci, 2022
Pang S, Deng C, Chen S.
europepmc   +1 more source

Interest rates, risk, and imperfect markets: puzzles and policies

, 1999
Joseph E. Stiglitz
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Research on Interest Rate Risk of Housing Mortgage Loan Based on Computer Simulation. [PDF]

Comput Intell Neurosci, 2021
Tang E.
europepmc   +1 more source