Results 171 to 180 of about 915,115 (354)

Jackknifing Bond Option Prices [PDF]

In continuous time specifications, the prices of interest rate derivative securities depend crucially on the mean reversion parameter of the associated interest rate diffusion equation.
Jun Yu, Peter C.B. Phillips
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Desarrollo histórico y perspectivas futuras de los mercados financieros derivados OTC [PDF]

In this paper, we’ll offer an overview about the main derivatives financial instruments. We’ll analyze the background and the present of the OTC (Over The Counter) derivative markets, specially swaps (interest rate swaps and currency swaps) and OTC ...
Antonio de la Torre, Antonio Trujillo, Cecilia Téllez   +2 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A Derivative-Based Framework for Real-Time Signal Processing and Event Detection in Impedance Flow Cytometry. [PDF]

Sensors (Basel)
Wurts B, Jindrich C, Gong Y, Ojih J, Hu M, Yin K, Shi L.   +6 more
europepmc   +1 more source

Derivatives Usage in Risk Management by US and German Non-Financial Firms: A Comparative Survey [PDF]

This paper is a comparative study of the responses to the 1995 Wharton School survey of derivative usage among US non-financial firms and a 1997 companion survey on German non-financial firms.
Gordon M. Bodnar, Gunther Gebhardt
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Synergistic design of an NiCo@BC-MOF derivative for enhanced energy storage and photocatalytic applications. [PDF]

RSC Adv
Arshad M, Khan ZUH, Zahid M, Abdullah MMS.   +3 more
europepmc   +1 more source

Derivatives and Depository Interest Rate Risk: An Empirical Analysis

, 1998
Arthur Hogan, David H. Malmquist
openalex   +1 more source

Hedging Strategies and Financial Risks [PDF]

Hedging strategies represent basic instrument used toward eliminating financial risk. Increasing volatility of financial markets and their globalization also lead to higher financial risks.
Zdenìk Zmeškal
core