Controlled Self-Immolative Release of β-Lapachone via an Optimized <i>para</i>-Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy. [PDF]
Becher JB +9 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Cyclic Tetraindoles with a Cyclooctatetraene Core: Controlling Planarity and Antiaromatic Character via N-Alkylation. [PDF]
Fujimoto K +3 more
europepmc +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
A brief visual evoked potential (VEP) modulation assessment of experience-dependent plasticity recorded via wireless dry-EEG headset in Phase 1 clinical units. [PDF]
McWilliams EC +10 more
europepmc +1 more source
An Analysis of OTC Interest Rate Derivatives Transactions: Implications for Public Reporting
Michael J. Fleming +4 more
openalex +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Mn<sup>2+</sup> Complex of a Fluorinated CDTA-Derivative: Stability, Inertness, and Paramagnetic <sup>1</sup>H, <sup>17</sup>O, and <sup>19</sup>F Relaxation Properties. [PDF]
Garda Z +4 more
europepmc +1 more source
Do Nonfinancial Firms Use Interest Rate Derivatives to Hedge?
Daniel M. Covitz, Steven A. Sharpe
openalex +1 more source

