Results 81 to 90 of about 915,115 (354)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Bank Lending in Dual Narratives: Economic Policy Uncertainty and Interest-Rate Derivatives
, 2023 Fang Zhao
openalex +2 more sources
Pricing interest rate derivatives under volatility uncertainty [PDF]
, 2022 Julian Hölzermann
openalex +1 more source
Nonparametric Estimation of Scalar Diffusion Processes of Interest Rates Using Asymmetric Kernels [PDF]
This paper proposes a nonparametric regression using asymmetric kernel functions for nonnegative, absolutely regular processes, and specializes this technique to estimating scalar diffusion models of spot interest rate.
Masayuki Hirukawa, Nikolay Gospodinov
core
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Fractional model applied to fermentation process kinetics
CQD Revista Eletrônica Paulista de Matemática, 2022 Biofuels are promising alternatives to partially or fully replace oil and natural gas-based fuels in combustion engines due to less environmental impact than fossil fuels. The production of biofuels through alcoholic fermentation in chemical reactors has
Hugo Pinheiro, Felix Silva Costa
doaj
Study on the Utilization and Impact of Financial Derivatives in Chinese Listed Companies [PDF]
SHS Web of ConferencesIn recent years, Chinese companies have been facing increasing risks in the financial market. In addition, international commodity prices fluctuated dramatically due to the geopolitical and global economic situation, further increasing the business risks
Sun Pengpeng
doaj +1 more source
Year-end seasonality in one-month LIBOR derivatives [PDF]
We examine the markets for one-month LIBOR futures contracts and options on those futures for a year-end price effect consistent with the previously identified year-end rate increase in one-month LIBOR.
Christopher J. Neely, Drew B. Winters
core
Interest rate swaps and economic exposure [PDF]
, 1997 The interest rate swap market has grown rapidly. Since the inception of the swap market in 1981, the outstanding notional principal of interest rate swaps has reached a level of $12.81 trillion in 1995.
Goswami, Gautam, Shrikhande, Milind
core