Results 151 to 160 of about 15,272,143 (302)
Interest Rate Modeling: A Matlab Implementation [PDF]
The aim of this work is to present a Matlab implementation of different methods for estimating the term structure of interest rate. More precisely, we implement the exponential functional form of Nelson-Siegel and polynomial spline methods (with or ...
Daniele Marazzina
core
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
The Interest Rate-Exchange Rate Link in the Mexican Float [PDF]
This paper examines empirically the interest rate-exchange rate link in the context of the Mexican experience with a floating exchange regime. The impulse response function derived from an ECM estimated by GMM reveals a lasting positive effect of a ...
Carlos A. Ibarra
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Exchange Rate, Interest Rate and Stock Market Price Volatility for Value-at-Risk Analysis [PDF]
The study derives a theoretically and empirically founded procedure for volatility estimation and forecasting of daily financial return series for use in value-at-risk model frameworks.
Ahlstedt, Monica
core
Retailer's inventory-based financing with bounded advance rates: Interplay between wholesale price contract and loan menu. [PDF]
PLoS OneDang Y, Tian J, Liao J, Tang M, Tian C.
europepmc +1 more source
Market risk and interest rate risk
, 2020 The course includes a set of materials collected for the OER project funded by the Colorado OER Council Grant (AY 2019-20). ; Course materials include sessions for FIN 670. ; Title supplied by instructor Tianyang Wang. ; Funded by the Colorado Open Educational Resources (OER) Grant 2018-2019.
openaire +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Methods for analyzing recurrent and terminal events considering composite and competing endpoints in clinical trials: a practical overview. [PDF]
BMC Med Res MethodolDuoerkongjiang A +3 more
europepmc +1 more source