Results 71 to 80 of about 2,832,778 (342)
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Introduction. The article is of relevance due to the beginning of the active phase of the race for the right to become the Democratic Party’s nominee for the 2020 United States presidential election.
Anna R. Fofanova
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To Warn or Not to Warn? Genetic Information, Families, and Physician Liability
Genetic testing raises a number of legal issues. Physicians providing genetic testing may be faced with questions related to privacy, confidentiality, and the duty to warn.
Jennifer L Gold
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Persuasion Games with Higher Order Uncertainty [PDF]
In persuasion games, it is well known that a perfectly revealing equilibrium may fail to exist when the decision maker is uncertain about the interested party\'s payoff-relevant information.
Frédéric KOESSLER
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RETRACTION: J. Chen, C. Chen, Y. Lin, Y. Su, X. Yu, Y. Jiang, Z. Chen, SY. Ke, SZ. Lin, L. Chen, Z. Zhang, and T. Zhang, “Downregulation of SUMO2 inhibits hepatocellular carcinoma cell proliferation, migration and invasion,” FEBS Open Bio 11, no. 6 (2021): 1771–1784. https://doi.org/10.1002/2211-5463.13173. The above article, published online on 14 May
wiley +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Exploiting common resources with capital-intensive technologies: the role of external forces [PDF]
This paper focuses on the interactions between local communities having at least some degree of informal claims over natural resources and firms interested in commercially exploiting such resources, explicitly allowing for interventions by third parties ...
ENGEL, STEFANIE, LÓPEZ, RAMÓN
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Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao +7 more
wiley +1 more source
Unità Popolare (UP) was a political and cultural movement inspired by the Action Party. It aimed to enhance the Italian political central area – so called “terza forza” – in order to contrast the bipolarization between cold war’s major fronts: the pro-US
Roberto Colozza è ricercatore post-doc presso il Centre d’Histoire de Sciences Po di Parigi nell’ambito di una borsa Marie Curie dell’UE (7° PQ).
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