Results 151 to 160 of about 7,569,689 (309)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Author Correction: Rapid modulation in music supports attention in listeners with attentional difficulties. [PDF]

Commun Biol
Woods KJP, Sampaio G, James T, Przysinda E, Cordovez B, Hewett A, Spencer AE, Morillon B, Loui P.   +8 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Genetic determinants of fatigue up to 2 years after radiotherapy in prostate cancer patients. [PDF]

Nat Commun
Heumann P, Aguado-Barrera ME, Jandu HK, Azria D, Briers E, Bultijnck R, Chang-Claude J, Choudhury A, Dunning AM, Fachal L, Fuentes-Ríos O, Gómez-Caamaño A, Gutiérrez-Enríquez S, Kaaks R, Kerns SL, Lambrecht M, Romero JCR, Rosenstein BS, De Ruysscher D, Schmidt ME, Sperk E, Stobart H, Symonds RP, Veldeman L, Veldwijk MR, Ward T, Webb A, West CML, Rancati T, Rattay T, Vega A, REQUITE Consortium, Talbot CJ, Seibold P.   +33 more
europepmc   +1 more source

Do Individual Interests Make A Difference? [PDF]

, 1988
Renninger, K. Ann
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Correction: Evaluation of an intermediate minor oral surgery service in Plymouth, England and implications for future commissioning. [PDF]

BDJ Open
Ziaebrahimi A, Witton R.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A Life Worth Sustaining? Bestowed Worth and Pediatric Care. [PDF]

Hastings Cent Rep
Kim DT, Yu X.
europepmc   +1 more source