Results 51 to 60 of about 998,889 (335)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Progress Toward Zero: The Climb to Sustainability - Interview with Ray Anderson [PDF]

open access: yes, 2012
Overhauling a wasteful and polluting company takes insight, knowledge, commitment, and courage. In this quest to achieve total sustainability by producing its product with no carbon emissions or landfill matter, Interface is well on its way to its 2020 ...
Gingerich, Elizabeth
core   +2 more sources

Quantum Information at the Interface of Light with Atomic Ensembles and Micromechanical Oscillators

open access: yes, 2011
This article reviews recent research towards a universal light-matter interface. Such an interface is an important prerequisite for long distance quantum communication, entanglement assisted sensing and measurement, as well as for scalable photonic ...
Hammerer, Klemens   +3 more
core   +1 more source

Cascading Quantum Light-Matter Interfaces

open access: yes, 2015
The ability to interface multiple optical quantum devices is a key milestone towards the development of future quantum networks that are capable of sharing and processing quantum information encoded in light. One of the requirements for any node of these quantum networks will be cascadability, i.e.
Namazi, Mehdi   +3 more
openaire   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Does Color Matter on Web User Interface Design

open access: yesCommIT Journal, 2017
Emotional advertising on the Internet such as websites and social media can be highly beneficial for Small Medium Enterprises (SMEs). However, not all of SMEs have a website that meets all of the principles of website design which are persuasive ...
Wirania Swasty, Andreas Rio Adriyanto
doaj   +1 more source

Research on evaluation of behavior safety level of miners based on cloud matter element theory

open access: yesMeikuang Anquan, 2021
In order to evaluate the behavior safety level of miner scientifically and reasonably, according to SHELL model, the evaluation index system of behavior safety level is established from five aspects: human factor, S-L interface factor, H-L interface ...
BAI Yanlong, CHEN Yu, LI Haili, BAI Changjiang, XI Long, XUE Yubi, PENG Jiajia, WANG Xin
doaj   +1 more source

Computational Tools for Supersymmetry Calculations

open access: yes, 2009
I present a brief overview of a variety of computational tools for supersymmetry calculations, including: spectrum generators, cross section and branching fraction calculators, low energy constraints, general purpose event generators, matrix element ...
Baer, Howard
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Power Conversion Interface for a Small-Capacity Photovoltaic Power Generation System

open access: yesEnergies, 2023
A power conversion interface for a small-capacity photovoltaic power generation system (PPGS) is proposed in this paper. The proposed power conversion interface is composed of a DC–DC converter (DDC), a battery pack and a buck–boost inverter (BBI).
Jinn-Chang Wu   +2 more
doaj   +1 more source

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