Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Dirac and Majorana neutrinos in matter
We consider the matter effects on neutrinos moving in background on the basis of the corresponding quantum wave equations. Both Dirac and Majorana neutrino cases are discussed.
A. Egorov+24 more
core +1 more source
Strong light-matter coupling in quantum chemistry and quantum photonics
In this article, we review strong light-matter coupling at the interface of materials science, quantum chemistry, and quantum photonics. The control of light and heat at thermodynamic limits enables exciting new opportunities for the rapidly converging ...
Johannes Flick, N. Rivera, P. Narang
semanticscholar +1 more source
Lasers that learn: The interface of laser machining and machine learning
Laser machining is a highly flexible non-contact fabrication method used extensively across academia and industry. Whilst simulations based on fundamental understanding offer some insight into the processes, the highly nonlinear interactions between ...
B. Mills, J. Grant-Jacob
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Constraining phases of quark matter with studies of r-mode damping in neutron stars
The r-mode instability in rotating compact stars is used to constrain the phase of matter at high density. The color-flavor-locked phase with kaon condensation (CFL-K0) and without (CFL) is considered in the temperature range 10^8K < T 10^{11} K, the ...
D. R. Lorimer+5 more
core +1 more source
PyUltraLight: a pseudo-spectral solver for ultralight dark matter dynamics [PDF]
PYULTRALIGHT simulates the dynamics of ultralight dark matter in a non-expanding background. PYULTRALIGHT can describe the evolution of several interacting ultralight dark matter halos or one or more halos orbiting a central, fixed Newtonian potential ...
Faber Edwards+3 more
semanticscholar +1 more source
Evidence That Microorganisms at the Animal-Water Interface Drive Sea Star Wasting Disease
Sea star wasting (SSW) disease describes a condition affecting asteroids that resulted in significant Northeastern Pacific population decline following a mass mortality event in 2013. The etiology of SSW is unresolved.
Citlalli A. Aquino+10 more
semanticscholar +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Soliton dynamics at an interface between uniform medium and nonlinear optical lattice
We study trapping and propagation of a matter-wave soliton through the interface between uniform medium and a nonlinear optical lattice (NOL). Different regimes for transmission of a broad and a narrow soliton are investigated.
Abdullaev, Fatkhulla Kh.+3 more
core +1 more source