Results 81 to 90 of about 3,380,586 (257)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Atomically dispersed Ce species adjacent to Ni nanoparticles as hydrogen scavengers for efficient catalytic ammonia decomposition

Nature Communications
CeO2 serves as an essential support or promoter for catalysts in ammonia decomposition, especially those based on Ni, yet its direct contribution to promoting NH3 activation and H2 desorption has rarely been understood.
Zizhen Xiao, Han Yan, Hao Lei, Jin-Cheng Liu, Haofan Lei, Tao Zhou, Sunpei Hu, Xiaohong Xu, Yongjie Ye, Liangwei Liu, Wenlong Wu, Ming Zuo, Ke Gong, Shui Lin, Xiaobao Li, Hui Zhang, Lili Han, Jie Zeng   +17 more
doaj   +1 more source

Focusing characteristics of a 4 πparabolic mirror light-matter interface

Journal of the European Optical Society-Rapid Publications, 2017
Background Focusing with a 4 π parabolic mirror allows for concentrating light from nearly the complete solid angle, whereas focusing with a single microscope objective limits the angle cone used for focusing to half solid angle at maximum.
Lucas Alber, Martin Fischer, Marianne Bader, Klaus Mantel, Markus Sondermann, Gerd Leuchs   +5 more
doaj   +1 more source

The Influence of Chronic Illness on Mental Health: Does the Age of the Patient Matter? [PDF]

, 2019
It is no secret that battling a chronic illness can impact an individual’s mental health, all while simultaneously harming their physical health. Although many say that this connection between chronic illness and mental health is obvious, we may still ...
Santostefano, Marianna
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Propagating interfaces in mixtures of active and passive Brownian particles

New Journal of Physics, 2016
The emergent collective dynamics in phase-separated mixtures of isometric active and passive Brownian particles is studied numerically in two-dimensions. A novel steady-state of well-defined propagating interfaces is observed, where the interface between
Adam Wysocki, Roland G Winkler, Gerhard Gompper   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Subsecond optically controlled domain switching in freestanding ferroelectric BaTiO3 membrane

Nature Communications
The quest to develop energy-efficient and fast optoelectronic control of memory devices is essential. In this respect, ferroelectric materials are gaining tremendous importance in information and communication technology.
Subhajit Pal, Lan-Tien Hsu, Haoying Sun, Sheng-Han Teng, Vivek Dwij, Emanuele Palladino, Yuefeng Nie, Samuel John, S. S. Prabhu, Anna Grünebohm, Joe Briscoe   +10 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

The role of surface-active macromolecules in the ice-nucleating ability of lignin, Snomax, and agricultural soil extracts [PDF]

Atmospheric Chemistry and Physics
Organic matter in agricultural soil dust can enhance dust's ice-nucleating ability relative to mineral dust and thus impact local cloud formation. But how is this organic matter able to nucleate ice?
K. A. Alden, K. A. Alden, K. A. Alden, P. Bieber, A. J. Miller, N. Link, B. J. Murray, N. Borduas-Dedekind   +7 more
doaj   +1 more source