Results 41 to 50 of about 96,296 (266)
To solve the problem of low interfacial bonding strength caused by the violent reaction of the titanium/stainless steel interface, the corrugated rolling-flat rolling (CFR) process was used to introduce inhomogeneous plastic deformation, and the titanium/
Wenjing Wang +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Interfacial area and interfacial transfer in two-phase systems. DOE final report [PDF]
In the two-fluid model, the field equations are expressed by the six conservation equations consisting of mass, momentum and energy equations for each phase. The existence of the interfacial transfer terms is one of the most important characteristics of the two-fluid model formulation.
Ishii, Mamoru +4 more
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Study on Interfacial Drag Model Based on Air-water Two-phase Flow Experiment in Vertical Pipe
The study of interfacial drag characteristics in two-phase flow is of great significance for the closure of key constitutive models in system program. In this paper, the air-water two-phase flow experiment covering bubbly flow and slug flow regimes was ...
ZHANG Luteng;HUANG Tao;ZHANG Muhao;ZHU Wen;HE Qingche;XU Wangtao;SUN Wan;MA Zaiyong;DING Shuhua;LI Zhongchun;PAN Liangming
doaj
Capillary pressure (Pc) and phase saturation (Sw) in two-phase flow are well known to be hysteretically related. Thermodynamically-derived multiphase flow theories conjecture that this hysteresis will be lifted if specific interfacial area (anw) is included as a new state variable to create a unique Pc - S - anw surface.
Godinez Brizuela, Omar +4 more
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
On the One-Dimensional Modeling of Vertical Upward Bubbly Flow
The one-dimensional two-fluid model approach has been traditionally used in thermal-hydraulics codes for the analysis of transients and accidents in water–cooled nuclear power plants.
C. Peña-Monferrer +5 more
doaj +1 more source

