Results 21 to 30 of about 88,074 (264)

Interfacial behaviour in Tunnel engineering [PDF]

, 2021
The force imparted on the soil by a tunnel boring machine can lead to catastrophic tunnel collapse. To help predict this behaviour the machine is modelled as point source in an elastic/plastic idealized soil with no cohesion. The model predicts a wedge shaped region of plasticity extending from the machine.
openaire   +1 more source

Organ-on-a-disc: A platform technology for the centrifugal generation and culture of microphysiological 3D cell constructs amenable for automation and parallelization

APL Bioengineering, 2020
Organ-on-a-chip (OoC) systems have evolved to a promising alternative to animal testing and traditional cell assays in drug development and enable personalization for precision medicine.
Stefan Schneider, Florian Erdemann, Oliver Schneider, Thomas Hutschalik, Peter Loskill   +4 more
doaj   +1 more source

Nanofiber scaffold gradients for interfacial tissue engineering [PDF]

Journal of Biomaterials Applications, 2012
We have designed a 2-spinnerette device that can directly electrospin nanofiber scaffolds containing a gradient in composition that can be used to engineer interfacial tissues such as ligament and tendon. Two types of nanofibers are simultaneously electrospun in an overlapping pattern to create a nonwoven mat of nanofibers containing a composition ...
Murugan, Ramalingam, Marian F, Young, Vinoy, Thomas, Limin, Sun, Laurence C, Chow, Christopher K, Tison, Kaushik, Chatterjee, William C, Miles, Carl G, Simon   +8 more
openaire   +2 more sources

Differentiation of physical and chemical cross-linking in gelatin methacryloyl hydrogels

Scientific Reports, 2021
Gelatin methacryloyl (GM) hydrogels have been investigated for almost 20 years, especially for biomedical applications. Recently, strengthening effects of a sequential cross-linking procedure, whereby GM hydrogel precursor solutions are cooled before ...
Lisa Rebers, Raffael Reichsöllner, Sophia Regett, Günter E. M. Tovar, Kirsten Borchers, Stefan Baudis, Alexander Southan   +6 more
doaj   +1 more source

Identification of two early blood biomarkers ACHE and CLEC12A for improved risk stratification of critically ill COVID-19 patients

Scientific Reports, 2023
In order to identify biomarkers for earlier prediction of COVID-19 outcome, we collected blood samples from patients with fatal outcomes (non-survivors) and with positive clinical outcomes (survivors) at ICU admission and after seven days.
Simone Kattner, Jan Müller, Karolina Glanz, Mehdi Manoochehri, Caroline Sylvester, Yevhen Vainshtein, Marc Moritz Berger, Thorsten Brenner, Kai Sohn   +8 more
doaj   +1 more source

Reconstitution of the membrane protein OmpF into biomimetic block copolymer–phospholipid hybrid membranes

Beilstein Journal of Nanotechnology, 2016
Structure and function of many transmembrane proteins are affected by their environment. In this respect, reconstitution of a membrane protein into a biomimetic polymer membrane can alter its function. To overcome this problem we used membranes formed by
Matthias Bieligmeyer, Franjo Artukovic, Stephan Nussberger, Thomas Hirth, Thomas Schiestel, Michaela Müller   +5 more
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Deciphering Electrolyte Dominated Na+ Storage Mechanisms in Hard Carbon Anodes for Sodium‐Ion Batteries

Advanced Science, 2023
Although hard carbon (HC) demonstrates superior initial Coulombic efficiency, cycling durability, and rate capability in ether‐based electrolytes compared to ester‐based electrolytes for sodium‐ion batteries (SIBs), the underlying mechanisms responsible ...
Guiyu Liu, Zhiqiang Wang, Huimin Yuan, Chunliu Yan, Rui Hao, Fangchang Zhang, Wen Luo, Hongzhi Wang, Yulin Cao, Shuai Gu, Chun Zeng, Yingzhi Li, Zhenyu Wang, Ning Qin, Guangfu Luo, Zhouguang Lu   +15 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Characterizing the growth of PHA-producing microorganisms on short-chain carboxylic acids

Microbial Cell Factories
Short-chain carboxylic acids are important chemical intermediates in anaerobic treatment or thermal hydrolysis of biowaste. They are a crucial precursor for the production of Polyhydroxyalkanoate (PHA) by various microorganisms. However, there is limited
Steven Leonhardt, Pravesh Tamang, Günter E. M. Tovar, Susanne Zibek   +3 more
doaj   +1 more source