Results 21 to 30 of about 53,407 (257)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Surface modification of carbon fibres with ammonium cerium nitrate for interfacial shear strength enhancement

open access: yes, 2022
Surface modification of carbon fibres with ammonium cerium nitrate for interfacial shear strength ...
AL Wilde (14569073)   +6 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Research on the Interaction Capability and Microscopic Interfacial Mechanism between Asphalt-Binder and Steel Slag Aggregate-Filler

open access: yes, 2022
To explore the applicability of steel slag porous asphalt mixture, the interaction capability and microscopic interfacial mechanism between asphalt-binder and steel slag aggregate-filler were investigated in this laboratory study.
Yunfeng Ning   +6 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A lotus-inspired Janus hybrid film enabled by interfacial self-assembly and in situ asymmetric modification

open access: yes, 2018
A lotus leaf inspired Janus hybrid film was exquisitely fabricated through a self-assembly process at the air/water interface with subsequent in situ asymmetric modification at the oil/water interface.
Huang, Youju   +8 more
core   +1 more source

Covalent sizing surface modification as a route to improved interfacial adhesion in carbon fibre-epoxy composites

open access: yes, 2021
Covalent sizing surface modification as a route to improved interfacial adhesion in carbon fibre-epoxy ...
DJ Eyckens (14451150)   +6 more
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

New approaches to casting hypereutectic Al-Si alloys to achieve simultaneous refinement of primary silicon and modification of eutectic silicon [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityHypereutectic Al-Si alloys are of increasing interest for applications that require a combination of light weight and high wear resistance, such as pistons ...
Al-Helal, Kawther
core  

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