Results 51 to 60 of about 725,251 (245)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Interfacial Tension Hysteresis of Eutectic Gallium-Indium [PDF]

, 2023
When in a pristine state, gallium and its alloys have the largest interfacial tensions of any liquid at room temperature. Nonetheless, applying as little as 0.8 V of electric potential across eutectic gallium indium (EGaIn) placed within aqueous NaOH (or
Nadimi, Sahar Rashid, Nithyanandam, Praneshnandan, Song, Minyung, Hillaire, Keith D., Kiani, Abolfazl, Daniels, Karen E., Dickey, Michael D.   +6 more
core   +1 more source

Aqueous Two-Phase Interfacial Assembly of COF Membranes for Water Desalination

Nano-Micro Letters, 2022
Aqueous two-phase system features with ultralow interfacial tension and thick interfacial region, affording unique confined space for membrane assembly.
Hongjian Wang, Jiashuai Zhao, Yang Li, Yu Cao, Ziting Zhu, Meidi Wang, Runnan Zhang, Fusheng Pan, Zhongyi Jiang   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Profiling and study of interfacial tension laden with crude lipid extract plant based as surfactant for food application [PDF]

, 2017
Crude lipid extract plant based namely SPLIP and PULIP are being introduced in this research as a potential surfactant with phospholipid and glycolipid components which playing an important role at the oil/water interface.
Zainol, N, Wolf, B, Gray, David
core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Reservoir brine, pressure, and CO₂ effects on brine-oil interfacial tension and rock wettability: Implications for EOR in carbonate rocks

Chemical Physics Impact
This study investigates the influence of brine composition, ionic species, pressure, and CO₂ injection on wettability and oil-brine interfacial tension in carbonate rocks from the Kurdistan Region of Iraq under simulated reservoir conditions.
Dana Abdulkareem Hasan, Azad Anugerah Ali Rasol, MNAM Norddin, Ramyar Suramairy, Ararat Rahimy, Maha R Hamoudi, Amanj W Khalid   +6 more
doaj   +1 more source