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Interactions of the Insect-Specific Palm Creek Virus with Zika and Chikungunya Viruses in Aedes Mosquitoes

open access: yesMicroorganisms, 2021
Palm Creek virus (PCV) is an insect-specific flavivirus that can interfere with the replication of mosquito-borne flaviviruses in Culex mosquitoes, thereby potentially reducing disease transmission.
Cassandra Koh   +3 more
doaj   +1 more source

Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite

open access: yesSensors, 2021
Hypochlorous acid (HOCl) generates from the reaction between hydrogen peroxide and chloride ions via myeloperoxidase (MPO)-mediated in vivo. As very important reactive oxygen species (ROS), hypochlorous acid (HOCl)/hypochlorite (OCl−) play a crucial role
Zhi-Guo Song   +3 more
doaj   +1 more source

Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti

open access: yesCell Reports, 2023
Summary: Arthropod-borne viruses (arboviruses) transmitted by Aedes aegypti mosquitoes are an increasing threat to global health. The small interfering RNA (siRNA) pathway is considered the main antiviral immune pathway of insects, but its effective ...
Sarah Hélène Merkling   +11 more
doaj   +1 more source

Ribosomal RNA (rRNA) sequences from 33 globally distributed mosquito species for improved metagenomics and species identification

open access: yeseLife, 2023
Total RNA sequencing (RNA-seq) is an important tool in the study of mosquitoes and the RNA viruses they vector as it allows assessment of both host and viral RNA in specimens. However, there are two main constraints.
Cassandra Koh   +9 more
doaj   +1 more source

Combined VEGFR and MAPK pathway inhibition in angiosarcoma

open access: yesScientific Reports, 2021
Angiosarcoma is an aggressive malignancy of endothelial cells that carries a high mortality rate. Cytotoxic chemotherapy can elicit clinical responses, but the duration of response is limited.
Michael J. Wagner   +12 more
doaj   +1 more source

The Protective Effects of Hydrogen Sulfide New Donor Methyl S-(4-Fluorobenzyl)-N-(3,4,5-Trimethoxybenzoyl)-l-Cysteinate on the Ischemic Stroke

open access: yesMolecules, 2022
In this paper, we report the design, synthesis and biological evaluation of a novel S-allyl-l-cysteine (SAC) and gallic acid conjugate S-(4-fluorobenzyl)-N-(3,4,5-trimethoxybenzoyl)-l-cysteinate (MTC).
Jing Fan   +12 more
doaj   +1 more source

Evidence For Long-Lasting Transgenerational Antiviral Immunity in Insects

open access: yesCell Reports, 2020
Summary: Transgenerational immune priming (TGIP) allows memory-like immune responses to be transmitted from parents to offspring in many invertebrates.
Juan A. Mondotte   +8 more
doaj   +1 more source

Differential Small RNA Responses against Co-Infecting Insect-Specific Viruses in Aedes albopictus Mosquitoes

open access: yesViruses, 2020
The mosquito antiviral response has mainly been studied in the context of arthropod-borne virus (arbovirus) infection in female mosquitoes. However, in nature, both female and male mosquitoes are frequently infected with insect-specific viruses (ISVs ...
Lionel Frangeul   +3 more
doaj   +1 more source

Interference Dissociation [PDF]

open access: yesCirculation, 1957
Contradirectional interference results when 2 stimuli arising in different foci in any part of the heart spread in opposite directions toward each other. Interference dissociation is defined as that type of dissociation which is due to repetitive contradirectional interference.
R, MILLER, R H, SHARRETT
openaire   +2 more sources

The biotin interference within interference suppressed immunoassays [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2021
AbstractBackgroundReports of false laboratory findings due to a biotin supplementation have raised concerns about the safety of immunoassays. According to current research, biotin is known to cause interference in immunoassays. Since up to 70% of medical decisions are based on laboratory results and the significantly increased intake of biotin ...
Payam Kabiri   +2 more
openaire   +3 more sources

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