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Interactions of the Insect-Specific Palm Creek Virus with Zika and Chikungunya Viruses in Aedes Mosquitoes

open access: yesMicroorganisms, 2021
Palm Creek virus (PCV) is an insect-specific flavivirus that can interfere with the replication of mosquito-borne flaviviruses in Culex mosquitoes, thereby potentially reducing disease transmission.
Cassandra Koh   +3 more
doaj   +1 more source

Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite

open access: yesSensors, 2021
Hypochlorous acid (HOCl) generates from the reaction between hydrogen peroxide and chloride ions via myeloperoxidase (MPO)-mediated in vivo. As very important reactive oxygen species (ROS), hypochlorous acid (HOCl)/hypochlorite (OCl−) play a crucial role
Zhi-Guo Song   +3 more
doaj   +1 more source

Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti

open access: yesCell Reports, 2023
Summary: Arthropod-borne viruses (arboviruses) transmitted by Aedes aegypti mosquitoes are an increasing threat to global health. The small interfering RNA (siRNA) pathway is considered the main antiviral immune pathway of insects, but its effective ...
Sarah Hélène Merkling   +11 more
doaj   +1 more source

Ribosomal RNA (rRNA) sequences from 33 globally distributed mosquito species for improved metagenomics and species identification

open access: yeseLife, 2023
Total RNA sequencing (RNA-seq) is an important tool in the study of mosquitoes and the RNA viruses they vector as it allows assessment of both host and viral RNA in specimens. However, there are two main constraints.
Cassandra Koh   +9 more
doaj   +1 more source

Combined VEGFR and MAPK pathway inhibition in angiosarcoma

open access: yesScientific Reports, 2021
Angiosarcoma is an aggressive malignancy of endothelial cells that carries a high mortality rate. Cytotoxic chemotherapy can elicit clinical responses, but the duration of response is limited.
Michael J. Wagner   +12 more
doaj   +1 more source

The Protective Effects of Hydrogen Sulfide New Donor Methyl S-(4-Fluorobenzyl)-N-(3,4,5-Trimethoxybenzoyl)-l-Cysteinate on the Ischemic Stroke

open access: yesMolecules, 2022
In this paper, we report the design, synthesis and biological evaluation of a novel S-allyl-l-cysteine (SAC) and gallic acid conjugate S-(4-fluorobenzyl)-N-(3,4,5-trimethoxybenzoyl)-l-cysteinate (MTC).
Jing Fan   +12 more
doaj   +1 more source

Evidence For Long-Lasting Transgenerational Antiviral Immunity in Insects

open access: yesCell Reports, 2020
Summary: Transgenerational immune priming (TGIP) allows memory-like immune responses to be transmitted from parents to offspring in many invertebrates.
Juan A. Mondotte   +8 more
doaj   +1 more source

Differential Small RNA Responses against Co-Infecting Insect-Specific Viruses in Aedes albopictus Mosquitoes

open access: yesViruses, 2020
The mosquito antiviral response has mainly been studied in the context of arthropod-borne virus (arbovirus) infection in female mosquitoes. However, in nature, both female and male mosquitoes are frequently infected with insect-specific viruses (ISVs ...
Lionel Frangeul   +3 more
doaj   +1 more source

Aspectual Errors in Romanian and Serbian ESP Learners Majoring in Tourism and Hospitality Management [PDF]

open access: yesActa Universitatis Sapientiae: Philologica, 2023
This paper examines the interference of the mother tongue, Serbian and Romanian, in the case of students of English for Tourism and Hospitality Purposes (ESP) at the university level in the field of verbal aspect.
Predrag Novakov, Mihaela Lazovic
doaj   +1 more source

Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut

open access: yesiScience, 2020
Summary: Diseases caused by mosquito-borne viruses have been on the rise for the last decades, and novel methods aiming to use laboratory-engineered mosquitoes that are incapable of carrying viruses have been developed to reduce pathogen transmission ...
Sarah Hélène Merkling   +9 more
doaj   +1 more source

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