Results 121 to 130 of about 2,658,048 (316)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Large System Analysis of Heterogeneous Cellular Networks With Interference Alignment

IEEE Access, 2018
In this paper, we conduct large system analysis of heterogeneous cellular networks (HCNs) which are modeled as a two-tier cellular network consisting of one macro base station (MaBS) and multiple micro base stations (MiBSs) distributed according to a ...
Xue Jiang, Baoyu Zheng, Wei-Ping Zhu, Lei Wang, Yulong Zou   +4 more
semanticscholar   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Interference alignment based on optimizing bit allocation with limited feedback in interfering MIMO-MAC networks

Tongxin xuebao, 2017
A novel limited feedback for interference alignment algorithm was proposed based on the disadvantages of traditional limited feedback interference alignment schemes for MIMO uplink.Unlike the traditional linear interference alignment,an iterative scheme ...
Xian-zhong XIE, Dan LI, Wei-jia LEI, Sen-lin ZHANG   +3 more
doaj   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Study of Interference Alignment

, 2013
The concept of interference alignment has recently become one of the importanttools to analyze the capacity of many multiuser communication networks,e.g. K-user interference channel, wireless X networks, multi hop interferencenetworks, etc.
Shokri Razaghi, Hazhir
core   +2 more sources

Study on Selection Diversity for MIMO 3-User Interference Channel with Interference Alignment

Mathematics
This paper explores selection diversity in the context of MIMO 3-user interference channels with interference alignment (IA), focusing on enhancing reliability through diversity order (DO) analysis.
Dongsup Jin, Xianglan Jin
doaj   +1 more source

Application of interference alignment in fullduplex D2D communications

MATEC Web of Conferences, 2018
As compared with the wireless half-duplex (HD) transmission, the wireless full-duplex (FD) transmission can potentially double the system throughput if the self-interference can be efficiently cancelled.
Ma Bei, Zhang Zhigang, Chen Ruirui
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source