Results 71 to 80 of about 567,285 (286)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

On the Optimality of Treating Interference as Noise: General Message Sets

, 2014
In a K-user Gaussian interference channel, it has been shown that if for each user the desired signal strength is no less than the sum of the strengths of the strongest interference from this user and the strongest interference to this user (all values ...
Geng, Chunhua, Jafar, Syed A., Sun, Hua
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A New Achievable Scheme for Interference Relay Channels

, 2013
We establish an achievable rate region for discrete memoryless interference relay channels that consist of two source-destination pairs and one or more relays. We develop an achievable scheme combining Han-Kobayashi and noisy network coding schemes.
Chung, Sae-Young, Kang, Byungjun, Lee, Si-Hyeon, Suh, Changho   +3 more
core   +1 more source

Bargaining Over the Interference Channel

2006 IEEE International Symposium on Information Theory, 2006
In this paper we analyze the interference channel as a conflict situation. This viewpoint implies that certain points in the rate region are unreasonable to one of the players. Therefore these points cannot be considered achievable based on game theoretic considerations.
Leshem, Amir, Zehavi, Ephraim
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Capacity Regions and Sum-Rate Capacities of Vector Gaussian Interference Channels

, 2009
The capacity regions of vector, or multiple-input multiple-output, Gaussian interference channels are established for very strong interference and aligned strong interference. Furthermore, the sum-rate capacities are established for Z interference, noisy
Chen, Biao, Kramer, Gerhard, Poor, H. Vincent, Shang, Xiaohu   +3 more
core   +2 more sources

Interference Alignment for the K-User MIMO Interference Channel [PDF]

IEEE Transactions on Information Theory, 2010
25 pages, 4 figures, Presented in part at ISIT 2010, submitted to IEEE Transactions on Information Theory, June ...
Akbar Ghasemi, Abolfazl Seyed Motahari, Amir Keyvan Khandani   +2 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The Ergodic Capacity of Phase-Fading Interference Networks

, 2012
We identify the role of equal strength interference links as bottlenecks on the ergodic sum capacity of a $K$ user phase-fading interference network, i.e., an interference network where the fading process is restricted primarily to independent and ...
Jafar, Syed A.
core   +1 more source