Results 141 to 150 of about 303,375 (325)

Aloe‐Emodin Targeting FOXC2 Disrupts NETs Formation and EMT‐Driven Postoperative Peritoneal Adhesion Through TGF‐β1‐Smad2/3 Pathway

open access: yesAdvanced Science, EarlyView.
Forkhead box protein C2 (FOXC2) is highlighted as a pivotal effector in postoperative peritoneal adhesion (PPA) formation. Mechanically, FOXC2 mediates NETs‐induced EMT alterations through the TGF‐β1‐Smad2/3 pathway. Aloe‐emodin (AE) ameliorates FOXC2‐driven fibrosis by blocking NETs formation and EMT changes through this pathway.
Lili Yang   +10 more
wiley   +1 more source

Simultaneous measurement of the absolute and relative time delay of a tiled-aperture coherent beam combination via the double-humped spectral beam interferometry

open access: gold, 2020
Keyang Liu   +8 more
openalex   +1 more source

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

open access: yesAdvanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang   +12 more
wiley   +1 more source

Interferometry [PDF]

open access: yes
The following recommended programs are reviewed: (1) infrared and optical interferometry (a ground-based and space programs); (2) compensation for the atmosphere with adaptive optics (a program for development and implementation of adaptive optics); and (
Begelman, Mitchell C.   +9 more
core   +1 more source

Wide‐Flow Aerosol Jet Printing Enables High‐Throughput, Ultra‐Low Aspect Ratio Patterning

open access: yesAdvanced Science, EarlyView.
Wide‐flow aerosol jet printing (WF‐AJP) employs an anisotropic nozzle design to generate planar aerosol jets, enabling millimeter‐scale deposition of highly uniform, ultra‐low aspect ratio (<1:6000) films with substantially reduced anisotropy in functional performance.
Zenan Niu   +8 more
wiley   +1 more source

De Novo Design of High‐Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor

open access: yesAngewandte Chemie, EarlyView.
Hybrid physics and deep‐learning enabled design methods identified miniprotein binders to Flpp3 (Francisella‐like lipoprotein), a key virulence factor from Francisella tularensis. Multiple candidates with nanomolar to picomolar binding affinities were obtained using yeast surface display screening and further experimental optimization.
Gizem Gokce‐Alpkilic   +18 more
wiley   +2 more sources

Electrically and Geometrically Tunable Photon Pair Entanglement from Ferroelectric Nematic Liquid Crystal

open access: yesAdvanced Science, EarlyView.
By exploiting the strong nonlinear optical response and controllable molecular ordering of ferroelectric nematic liquid crystals (FNLCs), these materials can serve as tunable sources of polarization‐entangled photons. Adjusting the sample geometry or applying an external electric field enables continuous control of the entanglement degree, advancing ...
Sara Klopčič   +3 more
wiley   +1 more source

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