Results 291 to 300 of about 300,339 (391)

Synthetic antibodies targeting EphA2 induce diverse signaling‐competent clusters with differential activation

open access: yesProtein Science, Volume 34, Issue 6, June 2025.
Abstract The receptor tyrosine kinase EphA2 interacts with ephrin (Efn) ligands to mediate bi‐directional signals that drive cellular sorting processes during tissue development. In the context of various cancers, EphA2 can also drive invasive metastatic disease and represents an important target for cancer therapeutics.
Jarrett J. Adams   +8 more
wiley   +1 more source

Molecular characterization of a synthetic neutralizing antibody targeting p67 of Theileria parva

open access: yesProtein Science, Volume 34, Issue 6, June 2025.
Abstract The Theileria parva sporozoite surface antigen p67 is a target of the bovine humoral immune response that generates antibodies capable of providing protection against subsequent infection. As a result, p67 has been the subject of efforts aimed at the development of an anti‐sporozoite subunit vaccine.
Shane Miersch   +10 more
wiley   +1 more source

Artificial Intelligence for Organoids Multidimensional Assessment

open access: yesSmartMat, Volume 6, Issue 3, June 2025.
This review provides a comprehensive analysis and discussion of the current applications of artificial intelligence (AI) technologies in the evaluation of organoids. It summarizes and synthesizes the primary methods and standards for organoid assessment, offering new insights for researchers engaged in the interdisciplinary field of AI and organoid ...
Yulin Mo   +5 more
wiley   +1 more source

Measurement of Englacial Velocity Fields With Interferometric Radio Echo Sounders

open access: yesJournal of Geophysical Research: Earth Surface, Volume 130, Issue 6, June 2025.
Abstract The surface velocity of ice sheets is now measured at high spatial and temporal resolutions by satellite‐borne platforms. The availability of this data has enabled rapid progress in both monitoring the evolution of ice sheets and understanding their underlying physical processes.
Thomas O. Teisberg   +3 more
wiley   +1 more source

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

open access: yesAngewandte Chemie, Volume 137, Issue 21, May 19, 2025.
A strategy for the conditional activation of therapeutic proteins utilizing removable peptide nucleic acid (PNA) masking groups is presented. Site‐specific installation of “Lock”‐PNAs containing a cleavage thioester linkage enabled steric blockage of receptor binding sites.
Bengt H. Gless   +6 more
wiley   +2 more sources

Semiconductor optical amplifier-based laser system for cold-atom sensors. [PDF]

open access: yesEPJ Quantum Technol
Kittlaus E   +7 more
europepmc   +1 more source

Experimental and computational methods for studying relaxation of aluminosilicate glasses: A review

open access: yesJournal of the American Ceramic Society, Volume 108, Issue 6, June 2025.
Abstract Relaxation plays a critical role in all glasses, especially those that undergo heat treatments for industrial applications. However, the fundamental mechanisms of relaxation are still poorly understood, especially in industrially relevant glasses such as aluminosilicate systems.
Brittney M. Hauke   +2 more
wiley   +1 more source

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