Results 161 to 170 of about 230,357 (266)

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Interferon alpha-inducible protein 27 (IFI27) inhibits hepatitis B virus (HBV) transcription through downregulating cellular transcription factor C/EBPα. [PDF]

J Virol
Yu X, Liu C-D, Shen S, Kim ES, Liu Z, Zhang H, Sun N, Liu Y, Martensen PM, Huang Y, Guo H.   +10 more
europepmc   +1 more source

The use of alpha interferon in the management of chronic myeloid leukaemia [PDF]

, 1997
Richard Richards, Christopher J. McCabe
openalex  

Effects of Interferon-.ALPHA.(IFN-.ALPHA.) as an Immunological Modifier on Post-Surgical Cell Mediated Immunosuppression in Dogs.

, 1994
Youko NAKADA, Hisako EZAKI, Shigeo Tanaka, Toshifumi Kosaka, Masato KUWABARA, Fusaoki KOIDE   +5 more
openalex   +2 more sources

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

Paradoxical pustular psoriasis induced by tumor necrosis factor inhibitor with elevated interferon-alpha in an ankylosing spondylitis patient: A case report. [PDF]

JAAD Case Rep
Khampaen T, Ploydaeng M.
europepmc   +1 more source

A Phase 2 Trial of Bevacizumab and High-dose Interferon Alpha 2B in Metastatic Melanoma

, 2011
Valerie P. Grignol, Thomas Olencki, Kiran Relekar, Cynthia Taylor, A. Kibler, Cheryl Kefauver, Lai Wei, Michael J. Walker, Helen X. Chen, Kari Kendra, William E. Carson   +10 more
openalex   +2 more sources

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, EarlyView.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

Regulation of interferon alpha production by the MAGUK-family protein CASK under H5N1 infection. [PDF]

Front Immunol
Huang JY, Sung PS, Hsieh SL.
europepmc   +1 more source

A FATAL CASE OF BILATERAL INTERSTITIAL PNEUMONIA (BLIP): INTERFERON ALPHA 2 A INDUCED.

, 2017
Balaji Ommurugan, Laxminarayana Kurady Bairy, Amita Priya, Joseph Thomas, Navin Patil   +4 more
openalex   +2 more sources