Results 11 to 20 of about 203,970 (332)

Clinical and serological manifestations associated with interferon-α levels in childhood-onset systemic lupus erythematosus [PDF]

open access: yesClinics, 2012
OBJECTIVE: To determine the serum levels of interferon alpha in childhood-onset systemic lupus erythematosus patients, their first-degree relatives and healthy controls and to evaluate the associations between serum interferon alpha and disease activity,
Appenzeller, Simone   +5 more
core   +8 more sources

Schwannoma response to interferon alpha

open access: yesInterdisciplinary Neurosurgery, 2017
While cranial nerve schwannomas are typically benign, slow growing tumors, they are associated with morbidity both from the neuropathies and neuralgias they can produce, as well as from the treatments used to address these tumors, typically surgery or radiation.
Jennifer Novak   +2 more
openaire   +4 more sources

Craniofaringioma cístico: quimioterapia intratumoral com interferon alfa [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2011
OBJECTIVE: To assess whether the cystic craniopharyngiomas can be controlled with the use of intratumoral applications of interferon alpha. METHOD: Nineteen patients with the diagnosis of cystic craniopharyngioma were treated with intratumoral ...
Capellano, Andrea Maria   +6 more
core   +5 more sources

CD8+ Lymphocytes from Healthy Blood Donors Secrete Antiviral Levels of Interferon-Alpha. [PDF]

open access: yesViruses, 2023
The adaptive immune response to viral infections features the antigen-driven expansion of CD8+ T cells. These cells are widely recognized for their cytolytic activity that is mediated through the secretion of cytokines such as perforin and granzymes ...
Teque F   +3 more
europepmc   +2 more sources

Use of Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma: A Retrospective Case Collection. [PDF]

open access: yesActa Derm Venereol, 2023
Mycosis fungoides and Sézary syndrome are rare and largely incurable types of cutaneous T-cell lymphoma with limited therapeutic options. In 1984 Bunn et al.
Gosmann J   +4 more
europepmc   +2 more sources

Production and Characterization of Polyclonal Antibodies Against Interferon Alpha in Mice

open access: yesBioscientific Review, 2021
The polyclonal antibodies are used extensively for research purposes in many areas of biology, such as immunoprecipitation, histochemistry, enzyme linked immunosorbent assays (ELISA), diagnosis of disease and western blots. Typically, an animal’s immune
Mehreen Fatima   +2 more
doaj   +1 more source

Interferon alpha-induced reduction in the values of myeloid-derived suppressor cells in melanoma patients [PDF]

open access: yesVojnosanitetski Pregled, 2015
Background/Aim. Interaction between tumor cells and host’s immunoregulatory cells in creation of microenvironment that supports tumor progression is the focus of numerous investigations in recent years.
Stanojević Ivan   +11 more
doaj   +1 more source

Interferons in Traumatic Brain and Spinal Cord Injury: Current Evidence for Translational Application

open access: yesFrontiers in Neurology, 2018
This review article provides a general perspective of the experimental and clinical work surrounding the role of type-I, type-II, and type-III interferons (IFNs) in the pathophysiology of brain and spinal cord injury. Since IFNs are themselves well-known
Francesco Roselli   +4 more
doaj   +1 more source

Pegylated interferon-alpha-2a for the treatment of ocular surface squamous neoplasia

open access: yesOman Journal of Ophthalmology, 2022
Ocular surface squamous neoplasia (OSSN) is the most common nonpigmented ocular surface neoplasm. Interferon-alpha (IFNα)-2b has been proved to be an effective immunotherapeutic agent to treat OSSN.
Murtuza Nuruddin   +2 more
doaj   +1 more source

Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion

open access: yesJournal of Translational Medicine, 2008
Background To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in 33 ...
Plebani Alessandro   +10 more
doaj   +1 more source

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