Regulation of interferon alpha production by the MAGUK-family protein CASK under H5N1 infection. [PDF]
Huang JY, Sung PS, Hsieh SL.
europepmc +1 more source
Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang+6 more
wiley +1 more source
BTK-Inhibition Enhances TLR-7-Mediated Interferon-Alpha Production in pDCs by Blocking the Inhibitory BDCA-2 Pathway. [PDF]
Ceglarek L+5 more
europepmc +1 more source
Family of human alpha-interferon-like sequences.
Sheldon I. Feinstein+6 more
openalex +1 more source
Opposite effects of recombinant interferon-alpha A and deoxycoformycin on adenosine deaminase activity in the Daudi B lymphoblastoid cell line [PDF]
CR Faltynek
openalex +1 more source
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu+10 more
wiley +1 more source
Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus. [PDF]
Stockfelt M+20 more
europepmc +1 more source
Alpha-interferon responses in cerebrospinal fluid of patients with suspected meningitis.
D O Ho-Yen, D Carrington
openalex +1 more source
Interferon alpha: recently approved in a number of countries for use in hairy cell leukaemia and/or Kaposi's sarcoma [PDF]
openalex +1 more source
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma+9 more
wiley +1 more source