Results 191 to 200 of about 224,020 (260)

BTK-Inhibition Enhances TLR-7-Mediated Interferon-Alpha Production in pDCs by Blocking the Inhibitory BDCA-2 Pathway. [PDF]

Eur J Immunol
Ceglarek L, Gerhards R, Boldrini V, Wichmann C, Peters A, Meinl E.   +5 more
europepmc   +1 more source

Engineering MnPt Bimetallic Nanozymes for Cascade Enzymatic Therapy and Enhanced Radio‐Immunotherapy

Advanced Science, EarlyView.
A CD44‐targeted MnPt bimetallic nanozyme (HD@MnO2) integrates multienzyme‐like activity with cGAS–STING activation to boost radio‐immunotherapy. Through cascade biocatalysis, it depletes glutathione, relieves hypoxia, and amplifies ROS, enhancing radiotherapy‐induced DNA damage and immunogenic cell death. The nanozyme promotes dendritic cell maturation
Wenyi Zhang, Yangyang Guo, Guoping Xu, Luhaoxiang Liu, Lin Chen, Cai Zhang, Yiming Li, Jianmin Li, Yang Zhao   +8 more
wiley   +1 more source

CD38-targeted attenuated interferon alpha immunocytokine activates both innate and adaptive immune cells to drive anti-tumor activity. [PDF]

PLoS One
Sampson JF, Zhang H, Zhang D, Bi M, Hinthorne A, Syed S, Zhang Y, Chattopadhyay N, Collins S, Pogue S, Björck P, Curley M.   +11 more
europepmc   +1 more source

Immunomodulatory Fibrous Scaffold with Dual Enzyme‐Mimic Activities Prevents Postsurgical Tumor Recurrence

Advanced Science, EarlyView.
A MnOx nanozyme‐functionalized electrospun fibrous scaffold is developed for postoperative therapy by leveraging its intrinsic physicochemical and immunomodulatory properties. Integrating POD‐ and CAT‐like activities, the scaffold induces immunogenic cell death, alleviates hypoxia, and reverses immunosuppression, while simultaneously recruiting and ...
Xiaoyi Zhao, Zhuolong Jiao, Yue Wang, Huimeng Gu, Longfei Li, Jian Song, Chen Xu, Jiajia Xue, Fu‐Jian Xu, Nana Zhao   +9 more
wiley   +1 more source

Different Biological Activities of Specific Interferon Alpha Subtypes

mSphere, 2019
Kim J. Hasenkrug, Kerry J. Lavender, Mario L. Santiago, Kathrin Sutter, Ulf Dittmer   +4 more
doaj   +1 more source

Dystonia during pegylated interferon alpha therapy in a case with essential thrombocythemia and cerebral infarction. [PDF]

Neurol Sci
Zhang P, Han B, Meng K, Cheng X, Liu Y, Sun Y, Hu F.   +6 more
europepmc   +1 more source

Alpha-interferon induced acute renal allograft rejection [PDF]

, 1995
Holley, JL, Johnson, JP, Jordan, M, Magnone, M, McCauley, J, Scantlebury, V, Shapiro, R, Starzl, T, Vivas, C   +8 more
core  

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of TCE‐secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

Optimized production and antiviral activity evaluation of recombinant chicken interferon-alpha using an improved Baculovirus expression system. [PDF]

Poult Sci
Zhang Y, Dong W, Li F, Meng K, Li G, Yuan X.   +5 more
europepmc   +1 more source

Plasma levels of Human Granulocytic Elastase-alpha-Proteinase Inhibitor Complex (E-alpha1PI) in Leukemia [PDF]

, 1984
Hiller, E., Jochum, Marianne
core