Results 201 to 210 of about 230,357 (266)

Systematic review and meta-analysis: de novo combination of nucleos(t)ide analogs and pegylated interferon alpha versus pegylated interferon alpha monotherapy for the functional cure of chronic hepatitis B. [PDF]

Front Pharmacol
Wei N, Zheng B, Cai H, Li N, Yang J, Liu M.   +5 more
europepmc   +1 more source

MCUB Inhibits PRKN‐Dependent Mitophagic Degradation of PD‐L1 to Promote Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, the overexpression of MCUB not only reduces mitochondrial calcium influx but also facilitates its binding to PRKN at Arg51, both mechanisms contribute to the impairment of PRKN‐mediated mitophagy. Consequently, the degradation of PD‐L1 is suppressed, leading to its stable expression on the tumor cell surface.
Yuan Huang, Chen Chen, Mingqiang Su, Dongqing Li, Jinge Zhang, Kuangye Long, Wenbin Nie, Shu Wei, Wei Chen, Haiyong Chen, Zhangfeng Zhong, Lina Hou, Wanlong Tan, Fei Li   +13 more
wiley   +1 more source

Tumor Integrin-Targeted Glucose Oxidase Enzyme Promotes ROS-Mediated Cell Death that Combines with Interferon Alpha Therapy for Tumor Control. [PDF]

Mol Cancer Ther
Stinson JA, Sheen A, Lax BM, Yang GN, Duhamel L, Santollani L, Fink E, Palmeri JR, Wittrup KD.   +8 more
europepmc   +1 more source

Extracts Ethanol of Centella Asiatica Enhance Interferon-gamma and Tumor Necrosis Factor-alpha in Macrophage Culture Infected by Mycobacterium Tuberculosis [PDF]

, 2012
Arifa Mustika, Roostantia Indrawati
openalex  

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

Advanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li, Weijia Chen, Mengxue Sun, Xinbo Ni, Qishan Ran, Xiaoyu Hu, Fang Cao, Wenwen Zeng   +7 more
wiley   +1 more source

EFFECTS OF TREATMENT WITH TEMSIROLIMUS VERSUS INTERFERON ALPHA ON SURVIVAL OF PATIENTS WITH METASTATIC RENAL CELL CARCINOMA - SINGLE-CENTER REAL-WORLD EXPERIENCE. [PDF]

Acta Clin Croat
Levakov I, Vojinov S, Maletin M, Jeremić D, Popov M, Levakov O, Grbić D.   +6 more
europepmc   +1 more source

Die Auswirkungen der Interferon-alpha Therapie auf das Leben von MelanompatientInnen

, 2010
Marlene Wild
openalex   +1 more source

Engineering Metal‐Organic‐Framework‐Based STING Nanoagonists for PROTAC‐Enhanced Cancer Chemo‐Metalloimmunotherapy

Advanced Science, EarlyView.
Schematic overview of PROTAC‐enhanced chemo‐metalloimmunotherapy, integrating senescence induction, multi‐modal STING pathway activation, PD‐L1 blockade, and immune amplification via coordinated PROTACs, metal ions, and chemotherapy to elicit robust antitumor immunity and circumvent immune evasion.
Zhenzhen Chen, Zhe Feng, Siyuan Wang, Jingjing Zhang   +3 more
wiley   +1 more source

The impact of hepatitis B surface antigen seroconversion on the durability of functional cure induced by pegylated interferon alpha treatment. [PDF]

Virol J
Zhang W, Chen J, Sun W, Xie N, Tian F, Ruan Q, Song J.   +6 more
europepmc   +1 more source

Differentiated T Lymphocytes and Cancer Cell Mitochondrial Metabolism to Enhance Radioimmunotherapy by a Biomimetic Nanozyme System

Advanced Science, EarlyView.
T cell membrane‐coated MgCO3/Fe‐CD nanozyme loaded with TEPP‐46 (TFMP) enhances breast cancer radioimmunotherapy by reprogramming mitochondrial metabolism in T cells and tumors. It targets PD‐L1, converts H2O2 into ROS, neutralizes acidity, and releases Mg2⁺/TEPP‐46 to boost T cell activation.
Hanyu Zhang, Yuhan Deng, Yantong Lu, Miao Wang, Kun Qiao, Zifan Yang, Shipeng Ning, Tong Liu   +7 more
wiley   +1 more source