Results 291 to 300 of about 203,970 (332)
Chicken Interferon-Alpha and -Lambda Exhibit Antiviral Effects against Fowl Adenovirus Serotype 4 in Leghorn Male Hepatocellular Cells. [PDF]
Int J Mol SciLai J +9 more
europepmc +1 more source
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
Proposal of a cutaneous lupus erythematosus-like keratinocyte model in vitro under local conditions using interferon-alpha and Poly I:C and its use in examining the therapeutic effects of tyrosine kinase 2 inhibitor. [PDF]
J DermatolKuba-Fuyuno Y +4 more
europepmc +1 more source
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Pharmacology & Therapeutics, 1995
The alpha-interferons (IFN-alpha) belong to a family of polypeptides comprising several subtypes. Using recombinant DNA technology, it has been possible to create IFN hybrids that provide novel combinations of the amino acid residues from the parental protein sequences.
S. Di Marco, M A Horisberger
openaire +3 more sources
The alpha-interferons (IFN-alpha) belong to a family of polypeptides comprising several subtypes. Using recombinant DNA technology, it has been possible to create IFN hybrids that provide novel combinations of the amino acid residues from the parental protein sequences.
S. Di Marco, M A Horisberger
openaire +3 more sources
Interferon-Alpha-Associated Monoarthritis [PDF]
Clinical Rheumatology, 2000 The therapeutic indications for interferons (IFNs) have increased in recent years to include many different diseases of viral and malignant origin. Autoimmune phenomena may occur with IFN therapy, but arthritis is uncommon. In this case report, we describe a patient who developed monoarthritis in the knee after IFN-alpha therapy for chronic hepatitis B
Şule Arslan +2 more
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The interferon-alpha revival in CML
Annals of Hematology, 2015Interferon-alpha (IFNα) was once the standard of frontline treatment for chronic myeloid leukemia (CML). Its pleiotropic mechanism of action in CML includes immune activation and specific targeting of CML stem cells. Early studies of IFNα in CML demonstrated that patients in chronic phase could attain extremely stable remissions, which correlated with ...
Jessica Mercer +2 more
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British Journal of Haematology, 1991
A number of studies are currently in progress to evaluate the use of interferon alpha, alone and in combination with conventional chemotherapy in patients with follicular lymphoma. The background to these is reviewed, together with currently available data about the potential role of interferon alpha in cutaneous T cell lymphoma.
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A number of studies are currently in progress to evaluate the use of interferon alpha, alone and in combination with conventional chemotherapy in patients with follicular lymphoma. The background to these is reviewed, together with currently available data about the potential role of interferon alpha in cutaneous T cell lymphoma.
openaire +3 more sources
Antibodies to interferon alpha in patients
1993A massive amount of information on interferons (IFNs) has been gathered since their original description as antiviral agents in 1957. Human IFNs have now been used clinically for over a decade and their therapeutic efficacy has been well established for some human neoplasias and viral diseases.
ANTONELLI, Guido, Dianzani F.
openaire +4 more sources