Results 61 to 70 of about 203,970 (332)
Effect of interferon-alpha on experimental septal fibrosis of the liver - study with a new model
Memorias do Instituto Oswaldo Cruz, 2001 Interferon-alpha is used in antiviral therapy in humans, mainly for viral hepatitis B and C. An anti-fibrotic effect of interferon has been postulated even in the absence of anti-viral response, which suggests that interferon directly inhibits ...
Marcia Maria de Souza +5 more
doaj +1 more source
Hepatitis B infection in Malta : a retrospective cross sectional study [PDF]
, 2012 Chronic Hepatitis B infection can lead to significant morbidity and mortality. Case notes of patients who tested positive for HBsAg between 1st Dec 2007 and 29th October 2009 were reviewed (n=197) . The results show that 2/3 (65%) of the study population
Caruana, Nichola +4 more
core
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Depression and interferon-alpha therapy [PDF]
British Journal of Psychiatry, 2000 In their case report, McAllister-Williams et al ([2000][1]) hypothesise that recurrence of major depression following treatment with interferon-alpha (IFNα) is related to its capacity to impair serotonin synthesis by inducing enzymes that degrade tryptophan and they cite in vitro evidence ...
Veronica O'Keane, Eugene M Cassidy
openaire +2 more sources
Журнал инфектологииRelevance: the annual incidence of acute respiratory infections (ARI) is in the lead in the structure of infectious pathology in the Russian Federation.
K. V. Kozlov +9 more
doaj +1 more source
Детские инфекции (Москва), 2015 The article demonstrates that the basis for pathogenesis of acute respiratory infection (ARI ) is a deficiency in a number of factors of virus protection.
V. V. Malinovskaya +3 more
doaj +1 more source
Apoptosis in the lungs of pigs infected with porcine reproductive and respiratory syndrome virus and associations with the production of apoptogenic cytokines [PDF]
, 2003 International audienceApoptosis was studied in the lungs of pigs during an infection with a European strain of porcine reproductive and respiratory syndrome virus (PRRSV) and it was examined if cytokines were involved in the induction of apoptosis ...
Labarque, Geoffrey +4 more
core +3 more sources
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Integrative Analysis of Immunological Data to Explore Chronic Immune T-Cell Activation in Successfully Treated HIV Patients. [PDF]
PLoS ONE, 2017 To unravel the complex relationships between cytomegalovirus-induced-, autoimmune-induced responses, microbial translocation and chronic immune activation (CIA) in successfully treated HIV-infected patients and to explore the mediating role of alpha ...
Marie-Quitterie Picat +10 more
doaj +1 more source
17β-Oestradiol Protects from Hepatitis C Virus Infection through Induction of Type I Interferon
Viruses, 2022 Background and Aims: Sex hormones are widely recognised to act as protective factors against several viral infections. Specifically, females infected by the hepatitis C virus display higher clearance rates and reduced disease progression than those found
Matteo Nazzareno Barbaglia +7 more
doaj +1 more source