The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon +21 more
wiley +1 more source
The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion [PDF]
Nasser Masroori +2 more
openalex +1 more source
The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging
Seungjin Ryu +6 more
openalex +2 more sources
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton +17 more
wiley +1 more source
Ischemic colitis induced on the injection day of pegylated-interferon for persistently normal ALT
青木 孝彦 +15 more
openalex +2 more sources
Low serum and peritoneal fluid concentration of interferon-γ–induced protein-10 (CXCL10) in women with endometriosis [PDF]
Letizia Galleri +6 more
openalex +1 more source
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann +26 more
wiley +1 more source
Promoter analysis of an interferon-inducible gene associated with macrophage activation. [PDF]
Charles M. Nicolet, Donna M. Paulnock
openalex +1 more source
Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu +14 more
wiley +1 more source
Paroxetine in interferon alfa 2B (IFN)-induced depression in chronic hepatitis C
Michael R. Kraus, Arne S. Schäefer
openalex +1 more source

