Results 61 to 70 of about 37,428 (161)

The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice [PDF]

open access: yes, 1996
MRL/MP-lpr/lpr (MRL/lpr) mice develop a spontaneous autoimmune disease. Serum from these mice contained significantly higher concentrations of nitrite/nitrate than serum from age-matched control MRL/MP-+/+ (MRL/+), BALB/c or CBA/6J mice.
Feng, G.J.   +4 more
core   +3 more sources

The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes. [PDF]

open access: yes, 2018
Activation of the inflammasome pathway is crucial for effective intracellular host defense. The mitochondrial network plays an important role in inflammasome regulation but the mechanisms linking mitochondrial homeostasis to attenuation of inflammasome ...
Alnemri, Emad S.   +9 more
core   +4 more sources

A Cross-Sectional Study Comparing the Frequency of Drug Interactions After Adding Simeprevir- or Sofosbuvir-Containing Therapy to Medication Profiles of Hepatitis C Monoinfected Patients. [PDF]

open access: yes, 2015
INTRODUCTION:This study compares the expected occurrence of contraindicated drug-drug interactions (XDDIs) when simeprevir (SIM)- or sofosbuvir (SOF)-containing therapy is added to medication profiles of patients with hepatitis C (HCV) monoinfection to ...
Bliss, Steven   +6 more
core   +1 more source

Clinical and epidemiologic efficacy of late interferon inductor in in the prevention of acute respiratory viral infections and influenza in 2017–2018 pre-epidemic period

open access: yesЛечащий Врач, 2021
Currently, great attention is paid to prevention of influenza and acute respiratory viral infections (ARVI). This article considers results of prospective observational study in prevention of influenza and ARVI among physicians.
V. A. Petrov   +5 more
doaj  

ANAFERON FOR KIDS: EFFECTIVENESS AND SAFETY OF THE THERAPEUTIC AND PREVENTIVE USE IN ACUTE INTESTINAL VIRAL INFECTIONS. LITERATURE REVIEW

open access: yesМедицинский совет, 2016
Acute infectious diarrheal diseases by the terminology of the World Health Organization or acute intestinal infections (AII) as they are called in Russia is a large group of acute infectious diseases characterized by development in patient of the ...
O. V. SHAMSHEVA
doaj   +1 more source

The current course of acute respiratory infections and the possibility of pathogenetic therapy.

open access: yesМедицинский совет, 2018
Acute respiratory viral infections (ARVI) are leading in the structure of the general morbidity of the population. To date, more than 200 viruses that affect the respiratory tract and ENT organs are known [1].
S. B. Krutikhina, E. A. Yablokova
doaj   +1 more source

Response of lymphocytes to a mitogenic stimulus during spaceflight [PDF]

open access: yes
Several studies were performed that demonstrate that immunological activities of lymphocytes can be affected by spaceflight or by models that attempt to simulate some aspects of weightlessness.
Sonnenfeld, Gerald
core   +1 more source

RSAD2: A pathogenic interferon-stimulated gene at the maternal-fetal interface of patients with systemic lupus erythematosus

open access: yesCell Reports Medicine
Summary: Pregnancy disorders in patients with autoimmune diseases or viral infections are often associated with an excessive response of type I interferons.
Xiaoyu Ding   +15 more
doaj   +1 more source

Cellular effects of microgravity [PDF]

open access: yes
Experiments are recounted that test the effects of microgravity on cells, from the 60's up to the present.
Morrison, Dennis R.
core   +1 more source

Circuitry of nuclear factor κB signaling [PDF]

open access: yes, 2006
Over the past few years, the transcription factor nuclear factor (NF)-κB and the proteins that regulate it have emerged as a signaling system of pre-eminent importance in human physiology and in an increasing number of pathologies. While NF-κB is present
Baltimore, David, Hoffmann, Alexander
core  

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