Results 61 to 70 of about 50,714 (355)
Modern therapy with interferonogens for acute respiratory viral infections in children
Медицинский совет, 2015 The article presents data on the place of the modern endogenous interferon inducers in the treatment and prevention of influenza and ARVI in children and the mechanisms of action.
Y. L. Mizernitskiy
doaj +1 more source
Interferon and Interferon Inducers in Protozoal Infections [PDF]
The Journal of General Physiology, 1970 Several interferon inducers (Newcastle disease virus, statolon, and poly rI:poly rC) as well as exogenous mouse interferon protect mice from sporozoite-induced Plasmodium berghei malaria, as long as they are administered before the end of the preerythrocytic phase of development of the parasite.
openaire +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Pharmacotherapy of Acute Bronchitis: Setting Priorities
Антибиотики и Химиотерапия, 2020 The publication analyses the data on the etiology of acute bronchitis, the possibilities of determining the C-reactive protein in the disease, and the study of the clinical efficacy of the use of endogenous interferon inducers during the treatment of ...
A. A. Zaitsev +5 more
doaj +1 more source
Вугрова хвороба:сучасні можливості лікування [PDF]
, 2010 Изучена эффективность использования макролидных антибиотиков и индукторов интерферона в комплексном лечении больных папуло-пустулезной формой угревой болезни. Установлено их позитивное влияние на клиническое течение заболевания, качество жизни пациентов,
Бєлай, І.М. +4 more
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
ACTIVATION OF SYNTHESIS OF ENDOGENOUS INTERFERON (REVIEW)
Разработка и регистрация лекарственных средств, 2019 The review is dedicated to the description of interferon inducers - new generation drugs created by Russian scientists as a result of the screening of thousands of high- and low-molecular synthetic and natural compounds.
V. V. Poloskov, F. I. Ershov
doaj
Антибиотики и Химиотерапия, 2022 The study of coronaviruses, including those capable of causing life-threatening diseases, continued for many decades. So did the study of interferons, as well as acridine acetic acid, which is a powerful interferon inducer.
P. V. MAZIN +4 more
doaj +1 more source
Interferon-α induced Raynaud's syndrome
Annals of Oncology, 2000 The cytokine interferon-alpha (IFN-alpha) is increasingly prescribed for a number of indications, especially viral hepatitis and several malignancies. Two patients are described who developed Raynaud's syndrome during treatment with IFN-alpha as adjuvant therapy for high-risk melanoma.
Kruit, Wim +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source