Results 211 to 220 of about 142,617 (267)

Targeting Renal IGFBP7 With Tetrahedral Framework Nucleic Acid‐Delivered siRNA Alleviates Acute Kidney Injury

open access: yesiNew Medicine, EarlyView.
A tFNA‐based siRNA delivery system targeting IGFBP7 effectively silences IGFBP7 expression and attenuates renal dysfunction, tubular injury, and cell death in both septic (CLP) and ischemic (I/R) murine models of acute kidney injury. ABSTRACT Objective Acute kidney injury (AKI) is a common and serious clinical condition, yet effective targeted ...
Shao‐qi Wu   +11 more
wiley   +1 more source

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

open access: yesInterdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong   +15 more
wiley   +1 more source

Profiles of White Nationalist Beliefs and Parenting in Conservative Parents: Implications for Adolescent Beliefs and Well‐Being

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Despite the growing threat of far‐right extremist and White nationalist beliefs in the United States, little is known about parenting factors associated with the development of these beliefs during adolescence. Using a person‐centered approach, this study examined how parental ideological beliefs, psychological control, and anger ...
Deborah Laible   +8 more
wiley   +1 more source

At the Crossroads: Intersection of Ethnic and Socioeconomic Backgrounds in the Interplay of Perceived Teacher Discrimination, Intergroup Attitudes, and Socioemotional Outcomes

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Perceived ethnic discrimination from teachers is associated with poorer adolescent adjustment, yet the mechanisms underlying these associations and the extent to which responses vary across the intersection of multiple social identities remain unclear.
Savaş Karataş   +2 more
wiley   +1 more source

The Imperative of De‐Marginalisation

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT On what basis, if any, can we legitimately justify spatial integrationist policies? Through a relational egalitarian lens, this article disentangles two phenomena that the wrong of residential segregation typically conflates: minimal segregation (mere clustering) and marginalisation (the production of unequal social standing through spatially ...
Elisabetta Gobbo
wiley   +1 more source

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