Results 31 to 40 of about 438,702 (304)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Part-level 3D shape generation driven by user intention inference with preferential Bayesian optimization

Scientific Reports
Advancements in generative artificial intelligence have introduced state-of-the-art models capable of producing impressive visual shape outputs.
Seung Won Lee, Jiin Choi, Kyung Hoon Hyun   +2 more
doaj   +1 more source

A Study of the Effect of Third Spaces Incorporating Smart Material and Structures on Student and Faculty Engagement and Well-being: A Case Study from the Amity University Campus in Dubai [PDF]

EPJ Web of Conferences
The project evaluates how Amity University in Dubai's staff members and students' academic satisfaction, well-being, and engagement are affected by informal third spaces that use smart materials and structures.
Salma Al-Zahabi, Mohammed Al-Kailani, Hanniya Noushad, Kamarunnisa Kamar   +3 more
doaj   +1 more source

Interior Life [PDF]

, 2010
Interior Life was curated by Tim Renshaw, Mary Maclean and Bernice Donszelmann who together form ‘Outside Architecture’. The aim of this project was to argue that interior space should not be negatively defined as a retreat from the public realm. Instead,
Donszelmann, Bernice, MacLean, Mary, Renshaw, Tim   +2 more
core  

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Cultural Determinants Within the Design Set Up of Kindergarten and Preschool Interiors: Assessment of Four Typologies in Terms of Their Spatial Formation

Megaron, 2017
The dynamic and complex nature of children's sense of physical environment (Lim, Barton, 2010) with respect to the location of the space concerning cultural conditions, relations, and parameters direct design criteria to meet pedagogic, physiologic, and ...
Meryem Yalçın, Ayşe Müge Bozdayı, Mehmet Hakan Ertek   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Digital Technology and Interior Architecture

Kocaeli Üniversitesi Mimarlık ve Yaşam Dergisi, 2020
Defined as the electronic demonstration of data on a screen, the digital concept has become a ubiquitous notion in the entire world and all aspects of life particularly after the onset of the 2000s. Video, camera, computer, mobile phone, television, watch, medical devices, laser gauge devices, electronic kitchen utensils, air conditioners and a myriad ...
DEMİRARSLAN, Deniz, DEMİRARSLAN, Oğuz
openaire   +4 more sources

Contributos para o estudo da arquitectura cisterciense, em Portugal, no âmbito do Projecto ORFEUS: forma e música [PDF]

, 2016
This communication reflects the work done in the Department of Civil Engineering and Architecture at the University of Beira Interior (Portugal), and still ongoing, in the framework of the project ORFEUS - The Tridentine Reform and music in the cloistral
Carlos, Jorge S., Conde, Antónia Fialho, Martins, Ana Maria Tavares, Reis, Carla, Rodrigues, Fabiel   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source