Results 51 to 60 of about 116,336 (250)
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
MathematicsIn this paper, a new full-Newton step feasible interior-point method for convex quadratic programming is presented and analyzed. The idea behind this method is to replace the complementarity condition with a non-negative weight vector and use the ...
Yongsheng Rao +2 more
doaj +1 more source
Jurnal Rekayasa Kimia & Lingkungan, 2014 A comparative study of Model Predictive Control (MPC) using active-set method and interior point methods is proposed as a control technique for highly non-linear pH process. The process is a strong acid-strong base system.
Syam Syafiie, Chia Yaw Kwan
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Interior Point Methods in Function Space [PDF]
SIAM Journal on Control and Optimization, 2005 A primal-dual interior point method for optimal control problems is considered. The algorithm is directly applied to the infinite-dimensional problem. Existence and convergence of the central path are analyzed, and linear convergence of a short-step path-following method is established.
openaire +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
An Efficient Penalty Method without a Line Search for Nonlinear Optimization
AxiomsIn this work, we integrate some new approximate functions using the logarithmic penalty method to solve nonlinear optimization problems. Firstly, we determine the direction by Newton’s method.
Assma Leulmi
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Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
A full-Newton step feasible interior-point algorithm for P∗(κ)-LCP based on a new search direction
Croatian Operational Research Review, 2016 In this paper, we present a full-Newton step feasible interior-point algorithm for a P∗(κ) linear complementarity problem based on a new search direction.
Behrouz Kheirfam, Masoumeh Haghighi
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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source