Results 51 to 60 of about 3,077 (212)

METHODOLOGY FOR INVESTIGATING THE PROBABILITY-TIME CHARACTERISTICS OF NETWORK ATTACKS IN THE SIMULATION MODELLING SOFTWARE ENVIRONMENT

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2018
. Objectives An analysis of open access literature sources and normative documents on the problem of information protection in automated systems was carried out.
Irina G. Drovnikova   +3 more
doaj   +1 more source

Hot dense silica glass with ultrahigh elastic moduli

open access: yesScientific Reports, 2022
Silicate and oxide glasses are often chemically doped with a variety of cations to tune for desirable properties in technological applications, but their performances are often limited by relatively lower mechanical and elastic properties.
Ningyu Sun   +4 more
doaj   +1 more source

Seismic anisotropy beneath the Chinese Mainland: Constraints from shear wave splitting analyses

open access: yesEarthquake Research Advances, 2021
We use earthquakes recorded by the China National Seismic Network from 2015 to 2019 and measure shear wave splitting parameters of SKS to study the anisotropic characteristics beneath the mainland of China.
Lingxia Gao, Daoyuan Sun
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Seismological evidence for a localized mushy zone at the Earth’s inner core boundary

open access: yesNature Communications, 2017
The existence of a mushy zone in the Earth’s inner core has been suggested, but has remained unproven. Here, the authors have discovered a 4–8 km thick mushy zone at the inner core boundary beneath the Okhotsk Sea, indicating that there may be more ...
Dongdong Tian, Lianxing Wen
doaj   +1 more source

The Geometric Interior in Real Linear Spaces [PDF]

open access: yesFormalized Mathematics, 2010
The Geometric Interior in Real Linear Spaces We introduce the notions of the geometric interior and the centre of mass for subsets of real linear spaces. We prove a number of theorems concerning these notions which are used in the theory of abstract simplicial complexes.
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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