Results 51 to 60 of about 94,153 (262)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Interior Experience of Architecture: An Emotional Connection between Space and the Body
Buildings, 2022 This paper provides a phenomenological understanding of interior space to explore the emotional connection between space and experience. It focuses on the significant aspects of interior space, considering how people experience interior space and which ...
Keunhye Lee
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
IDENTITY AND ITS EFFECT ON POSITIVE DESIGN FOR INTERIOR SPACE
Journal of Architecture, Art & Humanistic Science, 2021 Most of thinking operations when planning for interior space depend on solving architectural problems and designing the space neglecting the side of positive feelings of the user that affects his needs and acceptance to the interior space and therefore ...
Yosra El Harairy
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Waveform Energy Focusing Tomography With Passive Seismic Sources
Frontiers in Earth Science, 2022 By taking advantage of the information carried by the entire seismic wavefield, Full Waveform Inversion (FWI) is able to yield higher resolution subsurface velocity models than seismic traveltime tomography.
Yueqiao Hu +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Geophysical Research Letters, 2020 In the Nazca‐South American subduction zone, the subducted slab is flattened beneath northern Andes, called the Peruvian flat slab. The 2019 Mw 8.0 northern Peru intermediate‐depth normal‐faulting earthquake occurred at the leading edge of the Peruvian ...
Wei Liu, Huajian Yao
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Вестник Дагестанского государственного технического университета: Технические науки, 2018 . Objectives An analysis of open access literature sources and normative documents on the problem of information protection in automated systems was carried out.
Irina G. Drovnikova +3 more
doaj +1 more source