Results 41 to 50 of about 3,077 (212)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Interior Experience of Architecture: An Emotional Connection between Space and the Body
Buildings, 2022 This paper provides a phenomenological understanding of interior space to explore the emotional connection between space and experience. It focuses on the significant aspects of interior space, considering how people experience interior space and which ...
Keunhye Lee
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
IDENTITY AND ITS EFFECT ON POSITIVE DESIGN FOR INTERIOR SPACE
Journal of Architecture, Art & Humanistic Science, 2021 Most of thinking operations when planning for interior space depend on solving architectural problems and designing the space neglecting the side of positive feelings of the user that affects his needs and acceptance to the interior space and therefore ...
Yosra El Harairy
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
UTILISATION AND FURNISHING PATTERNS OF VERNACULAR HOUSING OF RĂȘINARI VILLAGE, SIBIU COUNTY, ROMANIA [PDF]
Pro Ligno, 2015 The paper presents research in the village of Răşinari, situated in the south region of Transilvania in Sibiu County, and investigated and evaluated a series of rural landmarks that could provide the necessary data to draw conclusions regarding the ...
Biborka BARTHA, Marina CIONCA
doaj
Waveform Energy Focusing Tomography With Passive Seismic Sources
Frontiers in Earth Science, 2022 By taking advantage of the information carried by the entire seismic wavefield, Full Waveform Inversion (FWI) is able to yield higher resolution subsurface velocity models than seismic traveltime tomography.
Yueqiao Hu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Geophysical Research Letters, 2020 In the Nazca‐South American subduction zone, the subducted slab is flattened beneath northern Andes, called the Peruvian flat slab. The 2019 Mw 8.0 northern Peru intermediate‐depth normal‐faulting earthquake occurred at the leading edge of the Peruvian ...
Wei Liu, Huajian Yao
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source