Results 81 to 90 of about 5,729,077 (300)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Subdivision of Seismicity Beneath the Summit Region of Kilauea Volcano: Implications for the Preparation Process of the 2018 Eruption

Geophysical Research Letters, 2021
Long‐period (LP), hybrid, and volcano‐tectonic (VT) seismicity are important indicators for tracking the evolution of volcanic processes. Here, we propose an unsupervised learning method to classify 5,949 seismic events in Kilauea volcano, Hawai'i ...
Xin Cui, Zefeng Li, Hui Huang
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

C2Ideas: Supporting Creative Interior Color Design Ideation with a Large Language Model [PDF]

International Conference on Human Factors in Computing Systems
Interior color design is a creative process that endeavors to allocate colors to furniture and other elements within an interior space. While much research focuses on generating realistic interior designs, these automated approaches often misalign with ...
Yihan Hou, Manling Yang, Hao Cui, Lei Wang, Jie Xu, Wei Zeng   +5 more
semanticscholar   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Rehabilitation of Heritage Buildings in Conflict Zones: A Case Study of Al-Khader Library in Gaza Strip and Its Impact on Sustainable Development

Buildings
Rehabilitating heritage buildings is a common practice in developed countries. In contrast, developing countries experiencing conflict lack the financial support and qualified experts to restore heritage buildings. This article focuses on the restoration
Dana Khalid Amro, Suheir Ammar
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Strong Hydro‐Related Localized Long‐Period Crustal Deformation Observed in the Plate Boundary Observatory Borehole Strainmeters

Geophysical Research Letters, 2018
Strong localized hydro‐related long‐period strain variations, with amplitude up to about 2,000 ns (nanostrain) (1–2 orders of magnitude larger than the tidal deformation), are observed in some Plate Boundary Observatory borehole strainmeters in Parkfield
Zhou Lu, Lianxing Wen
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source