Results 51 to 60 of about 4,632,061 (283)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Elements of interior architectural design against stylish approaches [PDF]

, 2014
The importance of this book is related to different reasons. Firstly it deals with interior architectural design that is a key topic in architectural practice even if it is a neglected subject in most schools of architecture nowadays as “interior ...
Delsante, Ioanni
core   +3 more sources

ARTISTIC-AESTHETIC EXPRESSIVENESS OF INTERNAL SPACE IN THE ARCHITECTURE OF CENTRAL ASIA

Вестник Дагестанского государственного технического университета: Технические науки, 2016
The article is dedicated to the peculiarities of the internal space composition in architecture of Central Asia. There are some main distinguishing features of artistic and aesthetic functions of this direction considered.
D. M. Bayramova
doaj   +1 more source

Author Correction: Velocity and density characteristics of subducted oceanic crust and the origin of lower-mantle heterogeneities

Nature Communications, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Wenzhong Wang, Yinhan Xu, Daoyuan Sun, Sidao Ni, Renata Wentzcovitch, Zhongqing Wu   +5 more
doaj   +1 more source

High seismic velocity structures control moderate to strong induced earthquake behaviors by shale gas development

Communications Earth & Environment, 2023
Moderate to strong earthquakes have been induced worldwide by shale gas development, however, it is still unclear what factors control their behaviors.
Junlun Li, Jian Xu, Haijiang Zhang, Wen Yang, Yuyang Tan, Fengshou Zhang, Lingyuan Meng, Yang Zang, Siyu Miao, Chang Guo, Zhenyue Li, Renqi Lu, Jianbao Sun   +12 more
doaj   +1 more source

Aseismic ridge subduction and flat subduction: Insights from three-dimensional numerical models

Earth and Planetary Physics, 2023
Flat subduction can significantly influence the distribution of volcanism, stress state, and surface topography of the overriding plate. However, the mechanisms for inducing flat subduction remain controversial.
Hui Zhao, Wei Leng
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Heavy magnesium isotopic signatures in arc lavas may be attributed to dehydration of subducting hydrated mantle

Communications Earth & Environment
Fluids released from subducting slabs profoundly affect mantle composition, rock melting points, and arc magma generation. However, identifying fluid sources (sediments, crust, or mantle) and their ascent paths remains challenging. Magnesium isotopes are
Xin Deng, Yi-Xiang Chen, Wenzhong Wang, Yonghui Li, Zicong Xiao, Zhongqing Wu   +5 more
doaj   +1 more source

Effect of Lights and Colors on the Environmental Perception and Legibility Using Augmented Reality Technology [PDF]

Iranian Evolutionary Educational Psychology Journal, 2020
One's cognitive perception of the environs is in direct relationship with their subjective mental image of the surroundings. Various elements influence the perception and legibility of the environment before human mind.
Ahmadreza Khalili, Hossein Soltanzadeh, S. Hadi Ghoddusifar   +2 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source