Results 71 to 80 of about 4,902,097 (286)

Seismological evidence for a localized mushy zone at the Earth’s inner core boundary

open access: yesNature Communications, 2017
The existence of a mushy zone in the Earth’s inner core has been suggested, but has remained unproven. Here, the authors have discovered a 4–8 km thick mushy zone at the inner core boundary beneath the Okhotsk Sea, indicating that there may be more ...
Dongdong Tian, Lianxing Wen
doaj   +1 more source

The Geometric Interior in Real Linear Spaces [PDF]

open access: yesFormalized Mathematics, 2010
The Geometric Interior in Real Linear Spaces We introduce the notions of the geometric interior and the centre of mass for subsets of real linear spaces. We prove a number of theorems concerning these notions which are used in the theory of abstract simplicial complexes.
openaire   +3 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Dwelling in public: a spatial justice and empathetic approach to interior public space and homelessness [PDF]

open access: yes, 2022
Social infrastructure has an important role in civic life, human interactions and a communities well-being. This practicum takes inspiration from the public library as one of the last forms of accessible interior public space that supports marginalized ...
Lipinsky, Katryna
core  

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Analysis of the regenerative design of Ru porcelain in hotels

open access: yesAl-Qadisiyah Journal for Engineering Science
Ru porcelain is part of China’s traditional culture, and in recent years, the use of Ru porcelain as a design element of hotel space has gradually increased. The primary purpose of this study is to explore the integration of Ru porcelain and contemporary
Cui   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Ecologies of the Interior

open access: yes, 2023
Introduction to Theme Issue This theme issue, Ecologies of the Interior, presents alternative models for thinking about the relationship between interior space, ecology, and economy.
Spankie, R.
core   +1 more source

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