Results 61 to 70 of about 1,228,916 (278)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
On the dimension of spline spaces on planar T-meshes [PDF]
We analyze the space of bivariate functions that are piecewise polynomial of bi-degree \textless{}= (m, m') and of smoothness r along the interior edges of a planar T-mesh.
Bernard Mourrain +1 more
core +4 more sources
Stellar Equilibrium in 2+1 Dimensions
The hydrostatic equilibrium of a $2+1$ dimensional perfect fluid star in asymptotically anti-de Sitter space is discussed. The interior geometry matches the exterior $2+1$ black-hole solution. An upper mass limit is found, analogous to Buchdahl's theorem
Giddings S, Jorge Zanelli, Norman Cruz
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Long‐period (LP), hybrid, and volcano‐tectonic (VT) seismicity are important indicators for tracking the evolution of volcanic processes. Here, we propose an unsupervised learning method to classify 5,949 seismic events in Kilauea volcano, Hawai'i ...
Xin Cui, Zefeng Li, Hui Huang
doaj +1 more source
Inverse Problems of Determining Sources of the Fractional Partial Differential Equations
In this chapter, we mainly review theoretical results on inverse source problems for diffusion equations with the Caputo time-fractional derivatives of order $\alpha\in(0,1)$. Our survey covers the following types of inverse problems: 1. determination of
Li, Zhiyuan +2 more
core +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Perancangan Interior Co-Working Space Di Surabaya [PDF]
Co-working is one solution to the problem of expensive land and limited work space with the increasing number of independent entrepreneurs and creative freelancers especially in big cities like Surabaya.
Yong, A. M. (Adelia)
core

