Results 51 to 60 of about 26,182 (287)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Result of intravitreal aflibercept injection for myopic choroidal neovascularization

BMC Ophthalmology, 2021
Background The current study aimed to evaluate the efficacy of intravitreal aflibercept injections as the primary treatment for subfoveal/juxtafoveal myopic choroidal neovascularization (CNV) by using optical coherence tomography (OCT). Optical coherence
Shih-Lin Chen, Pei-Ling Tang, Tsung-Tien Wu   +2 more
doaj   +1 more source

Self-interlacing polynomials [PDF]

, 2016
We describe a new subclass of the class of real polynomials with real simple roots called self-interlacing polynomials. This subclass is isomorphic to the class of real Hurwitz stable polynomials (all roots in the open left half-plane).
M. Tyaglov
semanticscholar   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Failure Mode of Depressive Osteochondral Fracture under Maximum Compressive Load: Studies of Normal, Osteoporotic, and Osteosclerotic Subchondral Bones

Siriraj Medical Journal, 2004
Objective : To determine the failure mode of depressive osteochondral fracture under the maximum compressive load. Design : An experimental cadaveric study.
Ekavit Keyurapan, Sirichai Wilasrusamee, Suchart Benjarusameerote, Thossart Harnroongroj   +3 more
doaj  

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

Advanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat, Mojtaba Karamimoghadam, Mohammadreza Lalegani Dezaki, Ali Zolfagharian, Giuseppe Casalino, Antonio Mateo, Mahdi Bodaghi   +6 more
wiley   +1 more source

Surface Morphology Prediction of Preforms in Rotational Braiding Process Based on Yarn Interlacement

Nanjing Hangkong Hangtian Daxue Xuebao
Rotary braiding is an efficient composite preform molding process， and the design of process parameters during braiding is crucial to the preform’s forming quality.
ZHU Xiangyu, SHAN Zhongde, SUN Zheng, GUO Zitong, WANG Yaoyao, LIU Jiale¹, GAO Yicen¹, SUN Xianpeng³   +7 more
doaj   +1 more source

Linear Sturm-Liouville problems with Riemann-Stieltjes integral boundary conditions [PDF]

Opuscula Mathematica, 2018
We study second-order linear Sturm-Liouville problems involving general homogeneous linear Riemann-Stieltjes integral boundary conditions. Conditions are obtained for the existence of a sequence of positive eigenvalues with consecutive zero counts of the
Qingkai Kong, Thomas E. St. George
doaj   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source