Results 1 to 10 of about 3,785 (95)
Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes [PDF]
, 2007 Adhesion molecules of the integrin beta1 family are thought to be involved in the malignant progression renal cell carcinoma (RCC). Still, it is not clear how they contribute to this process.Achiwa H, Anastassiou G, Blattner SM, Brenner W, Dufour S, Hegerfeldt Y, Hii CS, Markovic-Lipkovski J, Perlino E, Seftor RE, Yamada S +10 morecore +1 more sourceIFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13 [PDF]
, 2008 Background: IL-13 is a critical mediator of allergic asthma and associated airway hyperresponsiveness. IL-13 acts through a receptor complex comprised of IL-13Rα1 and IL-4Rα subunits with subsequent activation of signal transducer and activator of ...M Humbert, T Naseer, DS Robinson, SP Hogan, G Grunig, L Cohn, L Cohn, Z Zhu, Q Chen, R Leigh, M Yoshida, GK Hershey, D Kuperman, A Tomkinson, T Akimoto, DA Kuperman, H Ogata, MM Mentink-Kane, SO Rahaman, MO Daines, S Fichtner-Feigl, SP Hogan, O Tliba, K Espinosa, DS Faffe, PE Moore, S Zuyderduyn, SA Shore, Q Peng, V Govindaraju, G Grynkiewicz, J Kellner, JC Laporte, SJ Hirst, S Yamamoto, HL Dickensheets, NM Heller, T Sato, Z Huang, H Huang, J Ohara, F Syed, T Zheng, S Yasunaga, MO Daines, JA Losman, D Hebenstreit, H Dickensheets +47 morecore +3 more sourcesMapping determinants of cytokine signaling via protein engineering [PDF]
, 2018 Cytokines comprise a large family of secreted ligands that are critical for the regulation of immune homeostasis. Cytokines initiate signaling via dimerization or oligomerization of the cognate receptor subunits, triggering the activation of the Janus ...Alcami, Andrews, Andrews, Atanasova, Avalos, Ballinger, Becker, Boulanger, Boyman, Boyman, Boyman, Boyman, Brooks, Brown, Bulut, Charych, Chatterjee, Chill, Chomarat, Claudinon, Constantinescu, Constantinescu, Constantinescu, Cwirla, de, Elliott, Foster, Francois-Newton, Fujiwara, Gandhi, Gauzzi, Gent, German, Go, Haan, Heim, Heller, Ho, Ihle, Irandoust, Jaitin, Jaks, Jones, Junttila, Junttila, Kalie, Kalie, Kawahara, Keeler, Kelly-Welch, Kim, Klapper, Kovanen, Krause, Kurgonaite, LaPorte, Leonard, Levin, Levin, Levy, Li, Liang, Liao, Liu, Livnah, Lutz, MacNeil, Malka, Margolin, Marijanovic, Matthews, Mendoza, Mitra, Moore, Moraga, Moraga, Moraga, Moraga, Moraga, Mosser, Murray, Ohashi, Pattyn, Payelle-Brogard, Pellegrini, Pestka, Pestka, Piehler, Pillet, Porritt, Ramana, Rao, Rao, Rao, Reddy, Redpath, Remy, Richter, Rochman, Roisman, Romo, Ross, Rui, Schaeffer, Schindler, Schreiber, Schreiber, Shah, Shanafelt, Shanafelt, Smith, Smith, Spangler, Staerk, Steel, Subramaniam, Tenhumberg, Thomas, Urin, Vieira, Waldmann, Walter, Wang, Waters, Wills-Karp, Wilmes, Yamaoka, Yoon, You, Zhang, Zhang, Zhu +131 morecore +3 more sourcesMetabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats [PDF]
, 2013 Background: Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and mortality, however, its effect on cardiac gene expression pattern is unclear ...Csonka, Csaba, Csont, Tamás Bálint, Fekete, Veronika, Ferdinandy, Péter, Gyémánt, Nóra, Kocsis-Fodor, Gabriella, Pipis, Judit, Puskás, László, Szűcs, Gergő, Sárközy, Márta, Zvara, Ágnes +10 morecore +3 more sourcesActivation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation [PDF]
, 2016 yesInflammation of adipose tissue in obesity is associated with increased IL-1β, IL-6 and TNF-α secretion and proposed to contribute to insulin resistance.Alomar, Anna D. White, Bain, Benoit Viollet, Benziane, Bess, Bijland, Boyle, Brenner, Castanares-Zapatero, Chen, Claire Rutherford, Cohen, Coughlan, Delyth Graham, Dong, Erik A. Richter, Ewart, Flannery, Foretz, Fritzen, Galic, García-García, Gauthier, Green, Guigas, Göransson, Habinowski, Hawley, Ian P. Salt, Jeong, Jørgensen, Kim, Kim, Kwon, Laderoute, Lee, Lihn, Lihn, Lumeng, Meares, Miyokawa-Gorin, Moreno, Mottillo, Nerstedt, Qu, Rhian M. Touyz, Rios, Ross, Rotter, Rutherford, Sag, Salt, Sarah J. Mancini, Scott, Shibata, Silvia Bijland, Sun, Takahashi, Thiefes, Timothy M. Palmer, Viollet, Wang, Wang, Wang, Woods, Wu, Xu, Yang, Zaha, Zhang, Zhao +71 morecore +5 more sourcesPositively Correlated miRNA-miRNA Regulatory Networks in Mouse Frontal Cortex During Early Stages of Alcohol Dependence [PDF]
, 2013 Although the study of gene regulation via the action of specific microRNAs (miRNAs) has experienced a boom in recent years, the analysis of genome-wide interaction networks among miRNAs and respective targeted mRNAs has lagged behind.Blednov, Yuri A., Gorini, Giorgio, Harris, R. Adon, Mayfield, R. Dayne, Nunez, Yury O., Ponomareva, Olga N., Truitt, Jay M. +6 morecore +2 more sourcesGranulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review [PDF]
, 2009 Background
Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke.Alvarez-Dolado, Bath, Bath, Claire L. Gibson, Crain, Crossley, del Zoppo, Egger, England, Fisher, Gibson, Gibson, Gibson, Han, Hasselblatt, Hermann, Jendelova, Kawada, Kollmar, Komine-Kobayashi, Lan, Lee, Lees, Macleod, Matchett, Minnerup, Nagata, Philip M.W. Bath, Schabitz, Schneider, Schneider, Sehara, Sehara, Sena, Sevimli, Shuaib, Shyu, Shyu, Shyu, Six, Solaroglu, Solaroglu, Sprigg, Sprigg, Sykova, Taguchi, Timothy J. England, Toth, Vellenga, Wardlaw, Willmot, Yanqing, Zhao, Zhao, Zsebo, Zucali +55 morecore +2 more sourcesEtiology and Pharmacology of Neuropathic Pain [PDF]
, 2018 Injury to or disease of the nervous system can invoke chronic and sometimes intractable neuropathic pain. Many parallel, interdependent, and time-dependent processes, including neuroimmune interactions at the peripheral, supraspinal, and spinal levels ...Alles, SRA, Smith, PAcore +1 more sourceRole of AMP-activated protein kinase in adipose tissue metabolism and inflammation [PDF]
, 2013 AMPK (AMP-activated protein kinase) is a key regulator of cellular and whole-body energy balance. AMPK phosphorylates and regulates many proteins concerned with nutrient metabolism, largely acting to suppress anabolic ATP-consuming pathways while ...Ahmadian, An, Anthony, Arita, Arkan, Bain, Barnes, Barré, Bauwens, Berggreen, Bourron, Boyle, Boyle, Brooks, Buhl, Carey, Carling, Carling, Caton, Chakrabarti, Chaves, Chavez, Chen, Chen, Cheung, Cinti, Cool, Coppari, Daval, Daval, Ducharme, Duncan, Dzamko, Egan, Emerling, Eringa, Fazakerley, Fischer, Fisher, Flechtner-Mors, Foretz, Fox, Fryer, Gaidhu, Gaidhu, Gaidhu, Gaidhu, Galic, Garton, Gauthier, Gauthier, Geraghty, Giri, Glass, Grimaldi, Guigas, Gurriarán-Rodríguez, Gustafson, Habinowski, Hardie, Hawley, Hawley, Hawley, Henin, Hevener, Holmes, Hutchinson, Huypens, Ian P. Salt, Iglesias, Imamura, Iwatsubo, Jeon, Jeong, Jiao, Kanda, Kelly, Kim, Kitade, Koh, Kohlstedt, Koistinen, Kola, Kou, Kramer, Kristensen, Lee, Lee, Li, Lihn, Lihn, Lin, Lin, Liu, Lorente-Cebrián, Luo, López, Lönnqvist, MacDougald, Martínez-Agustin, Marzolla, McBride, McGee, McInnes, McInnes, Minokoshi, Mulligan, Narkar, Nguyen, Nishimura, Nishimura, Odegaard, Ojuka, Ojuka, Orci, Pagnon, Park, Peng, Perrotti, Peyton, Polakof, Pulinilkunnil, Rasmussen, Reihill, Reshef, Reshef, Rosen, Saberi, Sag, Sakamoto, Sakamoto, Sakaue, Sakoda, Salt, Salt, Salt, Samovski, Sano, Sarah J. Mancini, Schwenk, Scott, Shi, Silvia Bijland, Solinas, Sponarova, Steinberg, Steinberg, Su, Sullivan, Sun, Takekoshi, Tam, Tang, Turer, Vandanmagsar, Vats, Vaughan, Vila-Bedmar, Villena, Vingtdeux, Viollet, Vucetic, Wan, Wang, Wang, Wang, Watt, Winder, Woods, Wu, Xiao, Xu, Yamauchi, Yang, Yin, Yuen, Zhang, Zhang, Zhang, Zhang, Zhou, Zimmermann, Zmijewski +182 morecore +1 more source