Results 131 to 140 of about 1,334,419 (369)
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart +14 more
wiley +1 more source
Objective To evaluate the efficacy and safety of baricitinib in pediatric patients with active juvenile idiopathic arthritis–associated uveitis (JIA‐U) or chronic anterior antinuclear antibody–positive uveitis, who had an inadequate response to methotrexate (MTX) or biologic disease‐modifying antirheumatic drugs (bDMARDs).
Athimalaipet V. Ramanan +7 more
wiley +1 more source
Serum Soluble Mediator Signatures of Lupus Nephritis: Histologic Features and Response to Treatment
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histologic features and treatment response.
Andrea Fava +48 more
wiley +1 more source
Objective: To evaluate effects of docosahexaenoic acid-enriched phosphatidylcholine (DHA-PC) on cytokine production induced by lipopolysaccharide (LPS).
M Choi, J Y Baek, I Park, S Y Lim
doaj +1 more source
[Interleukin 2 receptor (Il-2): structure and function].
Interleukin 2 and its receptor play a crucial role in the growth and differentiation of many cells such as lymphocytes T and B, NK cells, macrophages and monocytes. Il-2 receptor (Il-2R) is involved in Il-2 induced cellular signalling. We discuss the Il-2R structure, function of three distinct subunits and the complex pathways that link the cell ...
A, Dmoszyńska, J, Roliński
openaire +1 more source
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti +19 more
wiley +1 more source
Interleukin‐2 (IL‐2) Receptor α, β and γ Subunit Expression as a Function of B‐Cell Lineage Ontogeny: the Use of IL‐2‐PE664Glu to Characterize Internalization via IL‐2 Receptor Subunits [PDF]
Ida Steinberger +3 more
openalex +1 more source
Ancient Cytokine Interleukin 15-Like (IL-15L) Induces a Type 2 Immune Response [PDF]
Takuya Yamaguchi +12 more
openalex +1 more source
Sex Differences in Medication Discontinuation in Axial Spondyloarthritis
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall +9 more
wiley +1 more source
Label-free detection of cytokines using optical microcavities [PDF]
Ultra-high-Q microresonators have demonstrated sensitive and specific chemical and biological detection. The sensitivity is derived from the long photon lifetime inside the cavity and specificity is achieved through surface functionalization. Here, ultra-
Armani, Andrea M., Fraser, Scott E.
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