Results 231 to 240 of about 1,240,457 (275)

Effects of Magnolia officinalis extract on the growth performance and immune function of weaned piglets. [PDF]

Porcine Health Manag
Zhang C, Liu B, Cui Z, Wu K, Huang H, Wang Y, Ma X, Tan B.   +7 more
europepmc   +1 more source

Genetically Diverse Mycobacterium tuberculosis Isolates Manipulate Inflammasome and Interleukin 1β Secretion Independently of Macrophage Metabolic Rewiring. [PDF]

J Infect Dis
Fernandes AI, Pinto AJ, Silvério D, Zedler U, Ferreira C, Duarte IF, Silvestre R, Dorhoi A, Saraiva M.   +8 more
europepmc   +1 more source

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Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4.

Science, 1993
The gamma chain of the interleukin-2 (IL-2) receptor is an indispensable subunit for IL-2 binding and intracellular signal transduction. A monoclonal antibody to the gamma chain, TUGm2, inhibited IL-2 binding to the functional IL-2 receptors and also ...
M. Kondo, T. Takeshita, N. Ishii, M. Nakamura, Sumiko Watanabe, Ken‐ichi Arai, K. Sugamura   +6 more
semanticscholar   +4 more sources

The regulatory, inflammatory, and T cell programming roles of interleukin-2 (IL-2).

Journal of Autoimmunity, 2008
Signaling through IL-2 induces the activation of pathways that lead to the proliferation, survival and cytokine production of effector T cells. However, through negative feedback mechanisms, internalization of the IL-2 receptor, induction of activation-induced cell death, and the generation of regulatory T cells, IL-2 also promotes the suppression of ...
Ruth Y. Lan, C. Selmi, M. Gershwin
semanticscholar   +5 more sources

Decreased Synthesis of Interleukin-2 (IL-2) in Insulin-dependent Diabetes Mellitus

Diabetes, 1984
Synthesis of interleukin-2 (IL-2) by lymphocytes from 26 insulin-dependent diabetic subjects (IDDM) was compared with that by lymphocytes from 24 nondiabetic control subjects. The control group produced 1.001 ± 0.071 U/ml (mean ± SEM). The IDDM group, containing patients diagnosed between 5 days and 10 yr before testing, produced only 0.59 ± 0.050 U/ml
K. Zier, M. Leo, R. Spielman, L. Baker
semanticscholar   +4 more sources

Role of Zinc in Interleukin 2 (IL‐2)‐Mediated T‐Cell Activation

Scandinavian Journal of Immunology, 1990
In a serum‐free culture containing no zinc, zinc enhanced the proliferation of T cells in response to interleukin 2 (lL‐2), and also the in vitro production of lL‐2 by T cells. Although the lymphocyte proliferation was partially inhibited by anti‐IL‐2 antibodies, it was completely inhibited by anti‐IL‐2 receptor (CD25) antibodies.
Y. Tanaka, S. Shiozawa, I. Morimoto, T. Fujita   +3 more
semanticscholar   +4 more sources

Phosphorylation of human interleukin-2 (IL-2) [PDF]

Molecular and Cellular Biochemistry, 1989
Human interleukin-2 (IL-2) is a lymphokine which is capable of activating lymphocytes and supporting the long-term in vitro growth of activated T cell clones. Recombinant human IL-2, expressed in either E. coli or cos cells, was shown to be phosphorylated by protein kinase C. Phosphorylated IL-2 synthesized in E.
Fazlur R. Khan, Louis E. Henderson, Hsiang-Fu Kung, Ida Calvert, Kuo-ping Huang, Shu-jing Wei, Terry D. Copeland, Eva Bekesi, Stephen Oroszlan, Raymond C. Sowder   +9 more
openaire   +2 more sources

Transcription and translation dependent induction of interleukin 2 (IL-2) and IL-2 receptors

Immunology Letters, 1984
Our previous findings on the expression of Interleukin 2 (IL-2) receptors have shown that under the influence of certain drugs, it was possible to dissociate IL-2 production from the appearance of IL-2 receptors on human peripheral blood lymphocytes (PBL).
A.L. de Weck, Y. Wang, Beda M. Stadler, C. Walker   +3 more
openaire   +3 more sources