Results 261 to 270 of about 1,240,457 (275)

High-dose interleukin-2 (IL-2) for the treatment of melanoma: safety considerations and future directions

Expert Opinion on Drug Safety, 2017
Stephen Marabondo, H. Kaufman
semanticscholar   +1 more source

Characterisation and expression analysis of interleukin 2 (IL-2) and IL-21 homologues in the Japanese pufferfish, Fugu rubripes, following their discovery by synteny

Immunogenetics, 2005
S. Bird, J. Zou, T. Kono, M. Sakai, J. M. Dijkstra, C. Secombes   +5 more
semanticscholar   +1 more source

Interleukin-2 (IL-2)

1995
Abstract IL-2 is a 15.5 kDa glycoprotein secreted primarily by activated T lymphocytes. The mature human IL-2 protein contains 133 amino acid residues, while the homologous proteins in other species contain 133 to 149 amino acids. The IL-2 primary translation product undergoes several post-translational processing steps that include ...
openaire   +1 more source

[Interleukin-2 (IL-2)].

Gan to kagaku ryoho. Cancer & chemotherapy, 1994
Interleukin-2, a polypeptide lymphokine that induces proliferation of antigen- or mitogen-stimulated T cells, was first described as "T-cell growth factor" by Morgan et al. in 1976. IL-2 is one of several lymphocyte-produced messenger regulatory molecules that modulate immunocyte function. The main secretory source of IL-2 is the T-helper cell. In 1983,
openaire   +1 more source

Activation of natural killer cells with interleukin 2 (IL‐2) and IL‐12 increases perforin binding and subsequent lysis of tumour cells

British Journal of Haematology, 2001
Christof Lehmann, M. Zeis, L. Uharek
semanticscholar   +1 more source

Tumour regression after intralesional injection of interleukin 2 (IL‐2) in bladder cancer. Preliminary report

International Journal of Cancer, 1984
G. Pizza, G. Severini, D. Menniti, C. de Vinci, Francesco Corrado   +4 more
semanticscholar   +1 more source

Lack of interleukin‐2 (IL‐2) expression and selective expression of IL‐10 mRNA in human renal cell carcinoma

International Journal of Cancer, 1995
H. Nakagomi, P. Pisa, E. Pisa, Y. Yamamoto, E. Halapi, K. Backlin, C. Juhlin, R. Kiessling   +7 more
semanticscholar   +1 more source

Induction of circulating tumor necrosis factor (TNFα) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients

Journal of Clinical Immunology, 1988
J. Mier, G. Vachino, J. Meer, R. Numerof, S. Adams, J. Cannon, H. Bernheim, M. Atkins, D. Parkinson, C. Dinarello   +9 more
semanticscholar   +1 more source

[Interleukin-2 (IL-2) and IL-2 receptor].

Nihon rinsho. Japanese journal of clinical medicine, 2000
T, Nishimura, T, Taniyama
openaire   +1 more source

The production and characterization of a monoclonal antibody to the interleukin 2 (IL-2) receptor

Cellular Immunology, 1982
E.M. Shevach, T.R. Malek
openaire   +2 more sources