Results 261 to 268 of about 1,628,367 (268)

The Effect of Interleukin 38 on Inflammation-induced Corneal Neovascularization

Current Molecular Medicine, 2019
Background: Angiogenesis is tightly linked to inflammation. Cytokines of interleukin 1 (IL-1) family are key mediators in modulating inflammatory responses. Methods: In this study, we examined the role of IL-38, a member of the IL-1 family, in mediating inflammation-induced angiogenesis.
Jiangli Zhu, Jianping Chen, Jing Zhang, Xiaopeng Li, Xiangling Liu, Eryan Kong, Shao Bo Su, Yan Wang, Zhongjian Zhang   +8 more
openaire   +3 more sources

Serum interleukin-38 and -41 levels as candidate biomarkers in male infertility

Immunology Letters, 2023
Interleukin (IL)-38 and IL-41 are novel cytokines, but their role in male infertility (MI) is unknown. The purpose of this study was to measure the levels of serum IL-38 and IL-41 in patients with MI and correlate these levels with semen indexes.Eighty-two patients with MI and 45 healthy controls (HC) were recruited for this study.
Chunhao, Rong, Linjie, Weng, Mingcai, Li, Liming, Zhou, Yan, Li   +4 more
openaire   +2 more sources

Interleukin‐38 alleviates hepatic steatosis through AMPK/autophagy‐mediated suppression of endoplasmic reticulum stress in obesity models

Journal of Cellular Physiology
Interleukin‐38 (IL‐38), recently recognized as a cytokine with anti‐inflammatory properties that mitigate type 2 diabetes, has been associated with indicators of insulin resistance and nonalcoholic fatty liver disease (NAFLD). This study investigated the
Jaw Long Sun, W. Cho, Hee-Suk Oh, A. M. Abd El‐Aty, Soon Auck Hong, Ji Hoon Jeong, T. Jung   +6 more
semanticscholar   +1 more source

Is Interleukin-38 a key player cytokine in atherosclerosis immune gene therapy?

Medical Hypotheses, 2019
Atherosclerosis, a chronic inflammatory disease of the arteries associated with lipids and other metabolic alterations is a leading cause of death all around the world and its rate is raising as a result of unhealthy lifestyles. Reports by World Health Organization indicate that 31% of all death occurrences are due to heart attacks and strokes.
Shabnam Pouyan, Abdolreza Esmaeilzadeh, Maryam Erfanmanesh   +2 more
openaire   +3 more sources

Interleukin-38 signaling

Reactome - a curated knowledgebase of biological pathways, 2017
JF Mora, Thawfeek M. Varusai
openaire   +2 more sources

The role of Interleukin-38 in modulating T cells in chronic Colitis: A mouse model study

Cytokine
Interleukin (IL)-38 belongs to the IL-36 subfamily within the IL-1 family. Patients with inflammatory bowel diseases (IBD) exhibit higher levels of IL-38 in their intestinal tissue compared to healthy controls, suggesting that IL-38 may play a role in the pathogenesis of IBD.
Ying, Xu, Xuan, Zhang, Shanshan, Liu, Nanfang, Qu, Yi, Gao, Changlong, Lu, Jingbo, Zhai, Junfeng, Zhu   +7 more
openaire   +2 more sources

N-terminally truncated interleukin-38

2016
The present invention pertains to an N-terminally truncated interleukin (IL)-38 protein, or functional variants thereof, as well as to nucleic acids and vectors encoding the truncated IL-38 peptide and recombinant cells comprising these nucleic acids or vectors.
FRAUNHOFER GES FORSCHUNG, JOHANN WOLFGANG GOETHE UNIVERSITÄT FRANKFURT AM MAIN   +1 more
openaire   +1 more source

Brief Report: Interleukin‐38 Exerts Antiinflammatory Functions and Is Associated With Disease Activity in Systemic Lupus Erythematosus

Arthritis & Rheumatology, 2015
I. Rudloff, J. Godsell, C. Nold-Petry, J. Harris, A. Hoi, E. Morand, M. Nold   +6 more
semanticscholar   +1 more source