Results 251 to 260 of about 1,122,542 (370)

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor. [PDF]

, 1988
Yuji Yamaguchi, Yukinori Hayashi, Yasuo Sugama, Yasusada Miura, Tadashi Kasahara, Satoshi Kitamura, Motomichi Torisu, Seiji Mita, A Tominaga, Kiyoshi Takatsu   +9 more
openalex   +1 more source

Reshape the Fates of Treg and CD8+T Cells Through IL‐2Rα by Synergizing Divergent Receptor‐Biased IL‐2 PEGylates

Advanced Science, EarlyView.
This study presents receptor‐biased IL‐2 PEGylates that selectively modulate IL‐2 receptor subunit interactions to enhance CD8⁺ T cell antitumor activity while curbing Treg activation and endothelial toxicity. The combined not‐α and not‐β variants balance immune stimulation and prevent T cell exhaustion, offering a novel, fine‐tuned approach for ...
Jiaqi Sun, Lingfeng Guo, Dezhong Ji, Mengfan Yu, Boyang Cheng, Xingxing Zhu, Yeshuang Yuan, Siyu Wu, Yuanjie Zhang, Wen Shi, Zhiqian Chen, Xindang Chu, Jiayu Hu, Liwen Hua, Yiming Wang, Yanning Zhu, Yu Mu, Hanwen Sun, Chuanling Zhang, Qi Wang, Sulong Xiao, Lihe Zhang, Bo Zhang, Demin Zhou   +23 more
wiley   +1 more source

RETRACTION: A Meta-Analysis of Interleukin-6 as a Valid and Accurate Index in Diagnosing Early Neonatal Sepsis. [PDF]

Int Wound J
europepmc   +1 more source

Correction: microRNA-4701-5p protects against interleukin-1β induced human chondrocyte CHON-001 cells injury via modulating HMGA1. [PDF]

J Orthop Surg Res
Zhang H, Chen C, Song J.
europepmc   +1 more source

Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. [PDF]

, 1988
M.E. Rothenberg, W F Owen, David S. Silberstein, Jennifer Woods, R J Soberman, K. Frank Austen, Richard L Stevens   +6 more
openalex   +1 more source

Mitigating Doxorubicin‐Induced Cardiotoxicity and Enhancing Anti‐Tumor Efficacy with a Metformin‐Integrated Self‐Assembled Nanomedicine

Advanced Science, EarlyView.
A novel self‐assembled nanomedicine (PMDDH) has been developed for the co‐delivery of doxorubicin and metformin, aiming to enhance the anti‐tumor efficacy of doxorubicin while alleviating its cardiotoxicity through the activation of cGAS‐STING and AMPK signaling pathways, respectively.
Jiaxin Huang, Jieru Yang, Yuanying Yang, Xiaofeng Lu, Juan Xu, Shan Lu, Hong Pan, Wenhu Zhou, Wenqun Li, Songwen Chen   +9 more
wiley   +1 more source

Plasma Immune Biomarkers Predictive of Progression to Active Tuberculosis in Household Contacts of Patients With Tuberculosis. [PDF]

J Infect Dis
Rajamanickam A, Ann Daniel E, Dasan B, Thiruvengadam K, Chandrasekaran P, Gaikwad S, Pattabiraman S, Bhanu B, Sivaprakasam A, Kulkarni V, Karyakarte R, Paradkar M, Shivakumar SVBY, Mave V, Gupta A, Hanna LE, Babu S.   +16 more
europepmc   +1 more source

Interleukin‐6 (IL‐6) functions as an in vitro autocrine growth factor in renal cell carcinomas [PDF]

, 1989
Shunji Miki, Masayuki Iwano, Yoshitsugu Miki, Masahiro Yamamoto, Bo Tang, Kiyoshi Yokokawa, Takao Sonoda, Toshio Hirano, Tadamitsu Kishimoto   +8 more
openalex   +1 more source

Interleukine [PDF]

, 2017
H. Renz, B. Gierten
openaire   +2 more sources

M6A Modified miR‐31‐5p Suppresses M1 Macrophage Polarization and Autoimmune Dry Eye by Targeting P2RX7

Advanced Science, EarlyView.
The upregulation of FTO in autoimmune dry eye suppresses the recognition of pri‐miR‐31 by DGCR8, thereby inhibiting the maturation of miR‐31‐5p and reducing its inhibitory effect on the target gene P2RX7. The activation of P2RX7 subsequently triggers the p38 MAPK signaling pathway and increases the level of M1‐related genes, thus exacerbating the ...
Lu Zhao, Xuejia Li, Min Gao, Lin Liu, Binyun Ma, Xun Liu, Jiachen Zhang, Ruoxuan Liu, Bei Du, Ruihua Wei, Hong Nian   +10 more
wiley   +1 more source